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EFFECT OF LASER IRIDOPLASTY ON PULSATILE OCULAR BLOOD FLOW IN PRIMARY ANGLE-CLOSURE GLAUCOMA AND PRIMARY ANGLE-CLOSURE SUSPECTS

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Date Issued:
2015
Abstract/Description:
Angle-closure glaucoma is a leading cause of blindness in the United States and around the world. New research has indicated that intraocular pressure is not the only risk factor associated with glaucomatous optic neuropathy. In recent years, a vascular deregulation in ocular blood flow has been considered a possible risk factor in glaucoma. A laser peripheral iridoplasty is a standard treatment option in non-pupillary block angle-closure glaucoma. The present study employed a secondary retrospective design and utilized patient's data from an ophthalmologist's practice. The purpose of this study was to examine the effect of laser peripheral iridoplasty on pulsatile ocular blood flow in primary angle-closure glaucoma and primary angle-closure suspects. A sample of 30 eyes from 17 patients was analyzed for this study. A significant increase in pulsatile ocular blood flow was found among primary angle-closure suspects. Additional data analysis was performed through SPSS software to examine the effect on these variables by age, sex and medical history as a total sample and in each group. Primary angle-closure suspects who were 51-60 years old showed a significant increase in intraocular pressure after laser treatment, however, primary angle-closure glaucoma patients who were 71-80 years old showed a significant decrease in intraocular pressure. Furthermore, a significant increase in pulsatile ocular blood flow was found in female subjects among primary angle-closure suspects, supporting the need for gender medicine research. Lastly, the pulsatile ocular blood flow increased significantly among primary angle-closure suspects who were also suffering from cardiovascular disease. Among primary angle-closure glaucoma patients who were suffering from both cardiovascular disease and diabetes mellitus, a significant decrease in intraocular pressure was observed.
Title: EFFECT OF LASER IRIDOPLASTY ON PULSATILE OCULAR BLOOD FLOW IN PRIMARY ANGLE-CLOSURE GLAUCOMA AND PRIMARY ANGLE-CLOSURE SUSPECTS.
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Name(s): Hill, Mathieu, Author
Saleh, Suha, Committee Chair
University of Central Florida, Degree Grantor
Type of Resource: text
Date Issued: 2015
Publisher: University of Central Florida
Language(s): English
Abstract/Description: Angle-closure glaucoma is a leading cause of blindness in the United States and around the world. New research has indicated that intraocular pressure is not the only risk factor associated with glaucomatous optic neuropathy. In recent years, a vascular deregulation in ocular blood flow has been considered a possible risk factor in glaucoma. A laser peripheral iridoplasty is a standard treatment option in non-pupillary block angle-closure glaucoma. The present study employed a secondary retrospective design and utilized patient's data from an ophthalmologist's practice. The purpose of this study was to examine the effect of laser peripheral iridoplasty on pulsatile ocular blood flow in primary angle-closure glaucoma and primary angle-closure suspects. A sample of 30 eyes from 17 patients was analyzed for this study. A significant increase in pulsatile ocular blood flow was found among primary angle-closure suspects. Additional data analysis was performed through SPSS software to examine the effect on these variables by age, sex and medical history as a total sample and in each group. Primary angle-closure suspects who were 51-60 years old showed a significant increase in intraocular pressure after laser treatment, however, primary angle-closure glaucoma patients who were 71-80 years old showed a significant decrease in intraocular pressure. Furthermore, a significant increase in pulsatile ocular blood flow was found in female subjects among primary angle-closure suspects, supporting the need for gender medicine research. Lastly, the pulsatile ocular blood flow increased significantly among primary angle-closure suspects who were also suffering from cardiovascular disease. Among primary angle-closure glaucoma patients who were suffering from both cardiovascular disease and diabetes mellitus, a significant decrease in intraocular pressure was observed.
Identifier: CFH0004874 (IID), ucf:45427 (fedora)
Note(s): 2015-12-01
B.S.
Health and Public Affairs, Dept. of Health Professions
Bachelors
This record was generated from author submitted information.
Subject(s): glaucoma
angle-closure glaucoma
pulsatile ocular blood flow
laser peripheral iridoplasty
Persistent Link to This Record: http://purl.flvc.org/ucf/fd/CFH0004874
Restrictions on Access: public 2015-12-01
Host Institution: UCF

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