Current Search: nature (x)
Pages
-
-
Title
-
Getting the Upper Hand: Natural Gesture Interfaces Improve Instructional Efficiency on a Conceptual Computer Lesson.
-
Creator
-
Bailey, Shannon, Sims, Valerie, Jentsch, Florian, Bowers, Clint, Johnson, Cheryl, University of Central Florida
-
Abstract / Description
-
As gesture-based interactions with computer interfaces become more technologically feasible for educational and training systems, it is important to consider what interactions are best for the learner. Computer interactions should not interfere with learning nor increase the mental effort of completing the lesson. The purpose of the current set of studies was to determine whether natural gesture-based interactions, or instruction of those gestures, help the learner in a computer lesson by...
Show moreAs gesture-based interactions with computer interfaces become more technologically feasible for educational and training systems, it is important to consider what interactions are best for the learner. Computer interactions should not interfere with learning nor increase the mental effort of completing the lesson. The purpose of the current set of studies was to determine whether natural gesture-based interactions, or instruction of those gestures, help the learner in a computer lesson by increasing learning and reducing mental effort. First, two studies were conducted to determine what gestures were considered natural by participants. Then, those gestures were implemented in an experiment to compare type of gesture and type of gesture instruction on learning conceptual information from a computer lesson. The goal of these studies was to determine the instructional efficiency (-) that is, the extent of learning taking into account the amount of mental effort (-) of implementing gesture-based interactions in a conceptual computer lesson. To test whether the type of gesture interaction affects conceptual learning in a computer lesson, the gesture-based interactions were either naturally- or arbitrarily-mapped to the learning material on the fundamentals of optics. The optics lesson presented conceptual information about reflection and refraction, and participants used the gesture-based interactions during the lesson to manipulate on-screen lenses and mirrors in a beam of light. The beam of light refracted/reflected at the angle corresponding with type of lens/mirror. The natural gesture-based interactions were those that mimicked the physical movement used to manipulate the lenses and mirrors in the optics lesson, while the arbitrary gestures were those that did not match the movement of the lens or mirror being manipulated. The natural gestures implemented in the computer lesson were determined from Study 1, in which participants performed gestures they considered natural for a set of actions, and rated in Study 2 as most closely resembling the physical interaction they represent. The arbitrary gestures were rated by participants as most arbitrary for each computer action in Study 2. To test whether the effect of novel gesture-based interactions depends on how they are taught, the way the gestures were instructed was varied in the main experiment by using either video- or text-based tutorials. Results of the experiment support that natural gesture-based interactions were better for learning than arbitrary gestures, and instruction of the gestures largely did not affect learning and amount of mental effort felt during the task. To further investigate the factors affecting instructional efficiency in using gesture-based interactions for a computer lesson, individual differences of the learner were taken into account. Results indicated that the instructional efficiency of the gestures and their instruction depended on an individual's spatial ability, such that arbitrary gesture interactions taught with a text-based tutorial were particularly inefficient for those with lower spatial ability. These findings are explained in the context of Embodied Cognition and Cognitive Load Theory, and guidelines are provided for instructional design of computer lessons using natural user interfaces. The theoretical frameworks of Embodied Cognition and Cognitive Load Theory were used to explain why gesture-based interactions and their instructions impacted the instructional efficiency of these factors in a computer lesson. Gesture-based interactions that are natural (i.e., mimic the physical interaction by corresponding to the learning material) were more instructionally efficient than arbitrary gestures because natural gestures may help schema development of conceptual information through physical enactment of the learning material. Furthermore, natural gestures resulted in lower cognitive load than arbitrary gestures, because arbitrary gestures that do not match the learning material may increase the working memory processing not associated with the learning material during the lesson. Additionally, the way in which the gesture-based interactions were taught was varied by either instructing the gestures with video- or text-based tutorials, and it was hypothesized that video-based tutorials would be a better way to instruct gesture-based interactions because the videos may help the learner to visualize the interactions and create a more easily recalled sensorimotor representation for the gestures; however, this hypothesis was not supported and there was not strong evidence that video-based tutorials were more instructionally efficient than text-based instructions. The results of the current set of studies can be applied to educational and training systems that incorporate a gesture-based interface. The finding that more natural gestures are better for learning efficiency, cognitive load, and a variety of usability factors should encourage instructional designers and researchers to keep the user in mind when developing gesture-based interactions.
Show less
-
Date Issued
-
2017
-
Identifier
-
CFE0007278, ucf:52192
-
Format
-
Document (PDF)
-
PURL
-
http://purl.flvc.org/ucf/fd/CFE0007278
-
-
Title
-
Hurricane Maria: A Qualitative Study of Recently Displaced Students to the State of Florida.
-
Creator
-
Cabrera, Esmeralda, Rivera, Fernando, Donley, Amy, Hinojosa, Melanie, University of Central Florida
-
Abstract / Description
-
Over the past ten years Puerto Rico has been experiencing a severe economic crisis that was worsened when Hurricane Maria made landfall on September 20, 2017. Maria hit Puerto Rico as a category 4 storm, devastating the whole island and its 3.4 millionresidents. Many students were left with minimal educational choices after Hurricane Maria hit Puerto Rico. Research on Latino/a students shows that they are met with unique experiences and challenges as they pursue higher education. The current...
Show moreOver the past ten years Puerto Rico has been experiencing a severe economic crisis that was worsened when Hurricane Maria made landfall on September 20, 2017. Maria hit Puerto Rico as a category 4 storm, devastating the whole island and its 3.4 millionresidents. Many students were left with minimal educational choices after Hurricane Maria hit Puerto Rico. Research on Latino/a students shows that they are met with unique experiences and challenges as they pursue higher education. The current study uses qualitative data to investigate what are the unique challenges and needs of displaced students from Puerto Rico? and what role does social capital play in confronting and navigating the challenges and needs associated with their transition to a new institutional setting? This study proposes to research the issues that many displaced Puerto Rican college student's face and add to the growing body of knowledge. It is important to understand how these recently displaced students will be affected by leaving behind, economic capital and cultural capital that they had built up in their communities on the island. Participation in the study included 9 participants from a large southeastern university that provided in-state tuition to displaced students for semi-structured qualitative interviews. Results revealed that family support was the main source of support for many of the students. Mentorship support was key in their educational success because the more support and encouragement from faculty led to a better transition. Support from peers was positively associated with a better transition and feeling of acceptance. Higher campus resources were positively associated with a better transition.
Show less
-
Date Issued
-
2019
-
Identifier
-
CFE0007606, ucf:52526
-
Format
-
Document (PDF)
-
PURL
-
http://purl.flvc.org/ucf/fd/CFE0007606
-
-
Title
-
Machine Learning from Casual Conversation.
-
Creator
-
Mohammed Ali, Awrad, Sukthankar, Gita, Wu, Annie, Boloni, Ladislau, University of Central Florida
-
Abstract / Description
-
Human social learning is an effective process that has inspired many existing machine learning techniques, such as learning from observation and learning by demonstration. In this dissertation, we introduce another form of social learning, Learning from a Casual Conversation (LCC). LCC is an open-ended machine learning system in which an artificially intelligent agent learns from an extended dialog with a human. Our system enables the agent to incorporate changes into its knowledge base,...
Show moreHuman social learning is an effective process that has inspired many existing machine learning techniques, such as learning from observation and learning by demonstration. In this dissertation, we introduce another form of social learning, Learning from a Casual Conversation (LCC). LCC is an open-ended machine learning system in which an artificially intelligent agent learns from an extended dialog with a human. Our system enables the agent to incorporate changes into its knowledge base, based on the human's conversational text input. This system emulates how humans learn from each other through a dialog. LCC closes the gap in the current research that is focused on teaching specific tasks to computer agents. Furthermore, LCC aims to provide an easy way to enhance the knowledge of the system without requiring the involvement of a programmer. This system does not require the user to enter specific information; instead, the user can chat naturally with the agent. LCC identifies the inputs that contain information relevant to its knowledge base in the learning process. LCC's architecture consists of multiple sub-systems combined to perform the task. Its learning component can add new knowledge to existing information in the knowledge base, confirm existing information, and/or update existing information found to be related to the user input. %The test results indicate that the prototype was successful in learning from a conversation. The LCC system functionality was assessed using different evaluation methods. This includes tests performed by the developer, as well as by 130 human test subjects. Thirty of those test subjects interacted directly with the system and completed a survey of 13 questions/statements that asked the user about his/her experience using LCC. A second group of 100 human test subjects evaluated the dialogue logs of a subset of the first group of human testers. The collected results were all found to be acceptable and within the range of our expectations.
Show less
-
Date Issued
-
2019
-
Identifier
-
CFE0007503, ucf:52634
-
Format
-
Document (PDF)
-
PURL
-
http://purl.flvc.org/ucf/fd/CFE0007503
-
-
Title
-
The Hermeneutics of the Hard Drive: Using Narratology, Natural Language Processing, and Knowledge Management to Improve the Effectiveness of the Digital Forensic Process.
-
Creator
-
Pollitt, Mark, Applen, John, Bowdon, Melody, Dombrowski, Paul, Craiger, John, University of Central Florida
-
Abstract / Description
-
In order to protect the safety of our citizens and to ensure a civil society, we ask our law enforcement, judiciary and intelligence agencies, under the rule of law, to seek probative information which can be acted upon for the common good. This information may be used in court to prosecute criminals or it can be used to conduct offensive or defensive operations to protect our national security. As the citizens of the world store more and more information in digital form, and as they live an...
Show moreIn order to protect the safety of our citizens and to ensure a civil society, we ask our law enforcement, judiciary and intelligence agencies, under the rule of law, to seek probative information which can be acted upon for the common good. This information may be used in court to prosecute criminals or it can be used to conduct offensive or defensive operations to protect our national security. As the citizens of the world store more and more information in digital form, and as they live an ever-greater portion of their lives online, law enforcement, the judiciary and the Intelligence Community will continue to struggle with finding, extracting and understanding the data stored on computers. But this trend affords greater opportunity for law enforcement. This dissertation describes how several disparate approaches: knowledge management, content analysis, narratology, and natural language processing, can be combined in an interdisciplinary way to positively impact the growing difficulty of developing useful, actionable intelligence from the ever-increasing corpus of digital evidence. After exploring how these techniques might apply to the digital forensic process, I will suggest two new theoretical constructs, the Hermeneutic Theory of Digital Forensics and the Narrative Theory of Digital Forensics, linking existing theories of forensic science, knowledge management, content analysis, narratology, and natural language processing together in order to identify and extract narratives from digital evidence. An experimental approach will be described and prototyped. The results of these experiments demonstrate the potential of natural language processing techniques to digital forensics.
Show less
-
Date Issued
-
2013
-
Identifier
-
CFE0005112, ucf:50749
-
Format
-
Document (PDF)
-
PURL
-
http://purl.flvc.org/ucf/fd/CFE0005112
-
-
Title
-
Stranger Species.
-
Creator
-
Latham, Devin, Thaxton, Terry, Stap, Donald, Kesler, Russ, University of Central Florida
-
Abstract / Description
-
Stranger Species is a collection of interconnected personal and lyrical essays that illustrate and dissect the biological and psychological forces that drive humans to act. While essays in the collection prove the narrator's need to believe that we are animals first and human beings second and that sex and persistence to survive are proof of our animalism, essays simultaneously counter-argue that humans(-)our emotions, weaknesses, and consciousness(-)are unique to our species, separating us...
Show moreStranger Species is a collection of interconnected personal and lyrical essays that illustrate and dissect the biological and psychological forces that drive humans to act. While essays in the collection prove the narrator's need to believe that we are animals first and human beings second and that sex and persistence to survive are proof of our animalism, essays simultaneously counter-argue that humans(-)our emotions, weaknesses, and consciousness(-)are unique to our species, separating us from the animal world. Throughout the collection, fear resonates that we do not control our desires and ultimately our lives, that biology and our deep seeded psychological inadequacies drive us blindly and often recklessly towards our species' survival never asking for our permission, leaving us to wonder why we do the strange things that we do. The narrator uses research and her experience to explore genetics, reproduction, desire, loneliness, binding societal constructions, control, and loss.
Show less
-
Date Issued
-
2014
-
Identifier
-
CFE0005516, ucf:50323
-
Format
-
Document (PDF)
-
PURL
-
http://purl.flvc.org/ucf/fd/CFE0005516
-
-
Title
-
EPISODIC MEMORY MODEL FOR EMBODIED CONVERSATIONAL AGENTS.
-
Creator
-
Elvir, Miguel, Gonzalez, Avelino, University of Central Florida
-
Abstract / Description
-
Embodied Conversational Agents (ECA) form part of a range of virtual characters whose intended purpose include engaging in natural conversations with human users. While works in literature are ripe with descriptions of attempts at producing viable ECA architectures, few authors have addressed the role of episodic memory models in conversational agents. This form of memory, which provides a sense of autobiographic record-keeping in humans, has only recently been peripherally integrated into...
Show moreEmbodied Conversational Agents (ECA) form part of a range of virtual characters whose intended purpose include engaging in natural conversations with human users. While works in literature are ripe with descriptions of attempts at producing viable ECA architectures, few authors have addressed the role of episodic memory models in conversational agents. This form of memory, which provides a sense of autobiographic record-keeping in humans, has only recently been peripherally integrated into dialog management tools for ECAs. In our work, we propose to take a closer look at the shared characteristics of episodic memory models in recent examples from the field. Additionally, we propose several enhancements to these existing models through a unified episodic memory model for ECAÃÂ's. As part of our research into episodic memory models, we present a process for determining the prevalent contexts in the conversations obtained from the aforementioned interactions. The process presented demonstrates the use of statistical and machine learning services, as well as Natural Language Processing techniques to extract relevant snippets from conversations. Finally, mechanisms to store, retrieve, and recall episodes from previous conversations are discussed. A primary contribution of this research is in the context of contemporary memory models for conversational agents and cognitive architectures. To the best of our knowledge, this is the first attempt at providing a comparative summary of existing works. As implementations of ECAs become more complex and encompass more realistic conversation engines, we expect that episodic memory models will continue to evolve and further enhance the naturalness of conversations.
Show less
-
Date Issued
-
2010
-
Identifier
-
CFE0003353, ucf:48443
-
Format
-
Document (PDF)
-
PURL
-
http://purl.flvc.org/ucf/fd/CFE0003353
-
-
Title
-
THE EDGE OF THINGS.
-
Creator
-
Koman, Robin, Hubbard, Susan, University of Central Florida
-
Abstract / Description
-
ABSTRACT The Edge of Things is what I like to call a love song to the dispossessed. Each of the eight stories in the collection is an examination of the lives of women who are exiled from modern American consumer culture, whether by circumstance or by choice. This separation brings them heartache, risk, and sometimes even hope. The collection is fueled by the landscape of Florida, observed at its most beautiful and most corrupted, from highways, landfills, and trailer parks to housing...
Show moreABSTRACT The Edge of Things is what I like to call a love song to the dispossessed. Each of the eight stories in the collection is an examination of the lives of women who are exiled from modern American consumer culture, whether by circumstance or by choice. This separation brings them heartache, risk, and sometimes even hope. The collection is fueled by the landscape of Florida, observed at its most beautiful and most corrupted, from highways, landfills, and trailer parks to housing developments, gardens, and secret forests. Setting is a constant source of revelation, the external landscape offering insight into the internal struggles of the characters. Regardless of age, race, or sexual orientation, the women of The Edge of Things find themselves moving toward, or just past, incredible changes in their lives. In "Seed of the Golden Mango", "Raising the Dead", and "The Girl Who Loved Bugs", young women deal with the loss of loved ones. The women of "Zyczenie", "It Cannot Hold", and "Wasp Honey" must deal with old losses in order to survive the realities of the outside world that they have long ignored. "The Edge of Things" and "The Secret Letters" both deal with love, and the consequences of an inability to communicate. In each of these tales I hope to present unforgettable characters, women whose journeys will haunt, reminding readers that on some level, the love song of the dispossessed calls to us all.
Show less
-
Date Issued
-
2008
-
Identifier
-
CFE0002024, ucf:47615
-
Format
-
Document (PDF)
-
PURL
-
http://purl.flvc.org/ucf/fd/CFE0002024
-
-
Title
-
INDIVIDUAL IDENTIFICATION OF POLAR BEARS BY WHISKER SPOT PATTERNS.
-
Creator
-
Anderson, Carlos, Waterman, Jane, University of Central Florida
-
Abstract / Description
-
Many types of ecological studies require identification of individual animals. I developed and evaluated an automated identification system for polar bears (Ursus maritimus) based on their whisker spot patterns. First, I measured the reliability of using whisker spot patterns for identification from polar bear photographs taken in western Hudson Bay. This analysis involved estimating the complexity of each whisker spot pattern in terms of its information content. I found that 98% of patterns...
Show moreMany types of ecological studies require identification of individual animals. I developed and evaluated an automated identification system for polar bears (Ursus maritimus) based on their whisker spot patterns. First, I measured the reliability of using whisker spot patterns for identification from polar bear photographs taken in western Hudson Bay. This analysis involved estimating the complexity of each whisker spot pattern in terms of its information content. I found that 98% of patterns contained enough information to be reliable, and this result varied little among three different observers. Based on these results, I implemented a computer-aided identification system for polar bears based on whisker spot pattern recognition. I used standard computer vision techniques to pre-process images and the Chamfer distance transform to compute similary scores between images. In addition, I evaluated the system by testing the effects of photographic quality and angle on system accuracy. I found that excellent and moderate quality/angle provided best results, with system accuracy of 90-95%. These findings suggest that individual identification of polar bears in the field based on whisker spot pattern variation is possible. Researchers studying polar bear behavior or estimating population parameters should benefit from this noninvasive technique.
Show less
-
Date Issued
-
2007
-
Identifier
-
CFE0001671, ucf:47207
-
Format
-
Document (PDF)
-
PURL
-
http://purl.flvc.org/ucf/fd/CFE0001671
-
-
Title
-
SYNTAX-BASED CONCEPT EXTRACTION FOR QUESTION ANSWERING.
-
Creator
-
Glinos, Demetrios, Gomez, Fernando, University of Central Florida
-
Abstract / Description
-
Question answering (QA) stands squarely along the path from document retrieval to text understanding. As an area of research interest, it serves as a proving ground where strategies for document processing, knowledge representation, question analysis, and answer extraction may be evaluated in real world information extraction contexts. The task is to go beyond the representation of text documents as "bags of words" or data blobs that can be scanned for keyword combinations and word...
Show moreQuestion answering (QA) stands squarely along the path from document retrieval to text understanding. As an area of research interest, it serves as a proving ground where strategies for document processing, knowledge representation, question analysis, and answer extraction may be evaluated in real world information extraction contexts. The task is to go beyond the representation of text documents as "bags of words" or data blobs that can be scanned for keyword combinations and word collocations in the manner of internet search engines. Instead, the goal is to recognize and extract the semantic content of the text, and to organize it in a manner that supports reasoning about the concepts represented. The issue presented is how to obtain and query such a structure without either a predefined set of concepts or a predefined set of relationships among concepts. This research investigates a means for acquiring from text documents both the underlying concepts and their interrelationships. Specifically, a syntax-based formalism for representing atomic propositions that are extracted from text documents is presented, together with a method for constructing a network of concept nodes for indexing such logical forms based on the discourse entities they contain. It is shown that meaningful questions can be decomposed into Boolean combinations of question patterns using the same formalism, with free variables representing the desired answers. It is further shown that this formalism can be used for robust question answering using the concept network and WordNet synonym, hypernym, hyponym, and antonym relationships. This formalism was implemented in the Semantic Extractor (SEMEX) research tool and was tested against the factoid questions from the 2005 Text Retrieval Conference (TREC), which operated upon the AQUAINT corpus of newswire documents. After adjusting for the limitations of the tool and the document set, correct answers were found for approximately fifty percent of the questions analyzed, which compares favorably with other question answering systems.
Show less
-
Date Issued
-
2006
-
Identifier
-
CFE0000985, ucf:46711
-
Format
-
Document (PDF)
-
PURL
-
http://purl.flvc.org/ucf/fd/CFE0000985
-
-
Title
-
THE EFFECT OF K562-IL21-2 PLASMA MEMBRANE PARTICLES ON THE PROLIFERATION OF NATURAL KILLER CELLS TO FIGHT CANCER.
-
Creator
-
Prophete, Michelle, Copik, Alicja, University of Central Florida
-
Abstract / Description
-
Immunotherapy has emerged as a current and future paradigm of cancer treatment, which utilizes the body's immune system to eradicate cancer. Natural Killer (NK) cells as part of the innate immune system have immense potential in their anti-tumor cytotoxic activities and host cell surveillance properties. NK cells comprise approximately five to fifteen percent of peripheral blood lymphocytes and can be proliferated in vitro using recently developed methods with co-cultures with feeder cells ...
Show moreImmunotherapy has emerged as a current and future paradigm of cancer treatment, which utilizes the body's immune system to eradicate cancer. Natural Killer (NK) cells as part of the innate immune system have immense potential in their anti-tumor cytotoxic activities and host cell surveillance properties. NK cells comprise approximately five to fifteen percent of peripheral blood lymphocytes and can be proliferated in vitro using recently developed methods with co-cultures with feeder cells (derived from engineered tumor cells) or plasma membrane (PM) particles, produced from the fore mentioned feeder cells, in combination with soluble cytokines. For efficient growth and maintenance of these NK cells, Interleukin-2 (IL-2) is utilized. IL-2 in solution, through receptor mediated signaling, stimulates proliferation of T-cells and NK cells. NK cells have lower responsiveness to IL-2 and consequently require a larger systemic dose to stimulate them as opposed to competing cell populations that have higher expression of receptors for IL-2, such as T-cells, which can have the effect of lower effective stimulation of NK cell growth. Such difference in the stimulatory capability of IL-2 toward NK cells and the short circulation lifetime of soluble IL-2 require higher dosages of soluble IL-2 for effective in vivo NK cell proliferation for therapeutic application against cancer, but is toxic. Therefore establishing another form of IL-2 delivery that improves its specific targeting to NK cells would be beneficial and may be crucial for novel therapeutic improvement. The Copik Laboratory has made an IL-2 fusion protein construct having a membrane anchor for expression of membrane-bound IL-2 on K562-41bbl-21 cells (K562-IL21). K562-IL21 cells are selectively recognized by NK cells and stimulate their proliferation and cytotoxicity. Hence, a K562-IL21 membrane-bound IL-2 form should be targeted to NK cells with IL-2 delivery. K562-IL21-2 cells were then used to prepare PM21-2 particles which have the potential to provide NK cell targeted, long-lived form of IL-2 for use as an injectable drug for in vivo adjuvant stimulation of NK cells. The presence of IL-2 on the in the PM21-2 particle product was verified by Western blot, and ELISA. Particle preparations from the modified K562 cells should possess characteristics that allow them to possibly replace soluble IL-2 and more specifically increase the numbers or anti-tumor activity of NK cell populations. The effect of PM21-2 particles was studied in in vitro culture based experiments, which tested the effectiveness the PM21-2 particles to induce selective NK cells expansion as compared to PM21 particles in the presence or absence of soluble IL-2.
Show less
-
Date Issued
-
2017
-
Identifier
-
CFH2000353, ucf:45918
-
Format
-
Document (PDF)
-
PURL
-
http://purl.flvc.org/ucf/fd/CFH2000353
-
-
Title
-
MULTIPLE ASPECTS OF NATURAL KILLER CELL EXPANSION IN RELEVANCE TO IMMUNOTHERAPY FOR HEMATOLOGIC MALIGNANCIES.
-
Creator
-
Colosimo, Dominic, Borgon, Robert, University of Central Florida
-
Abstract / Description
-
Natural Killer (NK) cells are a subset of lymphocytes that regulate adaptive immune responses and utilize "missing self" recognition to activate anti-tumor and anti-viral cytotoxicity. Clinical research, as well as murine and ex vivo models, have shown that a variety of NK cell applications have proven useful as immunotherapeutic treatments for patients with hematologic malignancies. However, the selective expansion of NK cells to yield relevant amounts of these lymphocytes has been a major...
Show moreNatural Killer (NK) cells are a subset of lymphocytes that regulate adaptive immune responses and utilize "missing self" recognition to activate anti-tumor and anti-viral cytotoxicity. Clinical research, as well as murine and ex vivo models, have shown that a variety of NK cell applications have proven useful as immunotherapeutic treatments for patients with hematologic malignancies. However, the selective expansion of NK cells to yield relevant amounts of these lymphocytes has been a major hurdle in the development of methods for clinical therapeutic use. Here, we demonstrate a novel ex vivo expansion method utilizing k562 leukemic cell lines and soluble cytokines as well as a novel method utilizing isolated plasma membranes of genetically engineered tumor cell lines that could be of relevance to in vivo NK cell expansion. Also, the ligand expression by canonical feeder cell lines used for NK cell expansion and our isolated plasma membranes were compared via ligand quantification by western blot quantification of 4-1BB ligand. In an adjunct study, we sought to better characterize these expansion environments by investigating the glucose metabolism of NK cells using fluorescent glucose analog 2-(N-(7-Nitrobenz-2-oxa-1, 3-diazol-4-yl)Amino)-2-Deoxyglucose (2-NBDG) and the glycolysis inhibitor 2-Deoxy-D-Glucose (2-DG).
Show less
-
Date Issued
-
2012
-
Identifier
-
CFH0004252, ucf:44917
-
Format
-
Document (PDF)
-
PURL
-
http://purl.flvc.org/ucf/fd/CFH0004252
-
-
Title
-
AMERICAN REVOLUTIONARY THINKERS: UNJUST WARS, LIMITED GOVERNMENT AND NATURAL RIGHTS.
-
Creator
-
Spera, Adam, Coverston, Harry, University of Central Florida
-
Abstract / Description
-
The conceptual bases of this thesis include the philosophical constructs of Just War Theory, limited government, and natural rights as applied to foreign policy. Just War Theory was originally articulated by St. Augustine and represents the requirements a nation must satisfy to wage war justly. Building upon the basis of Just War Theory, I then split the discussion into two main categories. The first is a historical look at certain American thinkers and their reactions to what they saw as...
Show moreThe conceptual bases of this thesis include the philosophical constructs of Just War Theory, limited government, and natural rights as applied to foreign policy. Just War Theory was originally articulated by St. Augustine and represents the requirements a nation must satisfy to wage war justly. Building upon the basis of Just War Theory, I then split the discussion into two main categories. The first is a historical look at certain American thinkers and their reactions to what they saw as unjust wars based in their strong idealistic goals for humanity. The second is a critical examination of American foreign policy based upon the analytical model arising from these American thinkers. The thesis concludes with an examination of contemporary applications of this analysis with an examination of recent wars that have taken place in the Middle East and an assessment of their just or unjust nature. My historical research examines the arguments of Thomas Paine, Emma Goldman, Henry David Thoreau, and Martin Luther King, Jr. I will review each thinker to highlight their criticisms of the unjust wars in which America has been involved from the 18th Century to the 21st Century. A secondary goal of this research is to trace a pattern of idealistic thinking that is present in American Revolutionary thought. These ideals refer to notions of natural rights, social liberty, economic freedom, and the constant pursuit of justice. By using the established arguments put forth by these four American thinkers, I argue that another unjust war will only bring misery to America and any other nation involved. iii Finally, my contemporary research develops the CIA term "blowback" and its effect on American foreign policy. By applying the theory of blowback to the current military disputes in which the United States has been or could be involved, I attempt to persuade the reader to resist the notion of engaging in another war. Historically unjust wars have never improved the standard of living for the American citizen and have served to suppress the inherent natural rights of the human beings involved. In conclusion, I combine contemporary and historical arguments to highlight the continuing stream of injustice that exists in American foreign policy.
Show less
-
Date Issued
-
2012
-
Identifier
-
CFH0004196, ucf:44854
-
Format
-
Document (PDF)
-
PURL
-
http://purl.flvc.org/ucf/fd/CFH0004196
-
-
Title
-
REAL-TIME REALISTIC RENDERING OF NATURE SCENES WITH DYNAMIC LIGHTING.
-
Creator
-
Boulanger, Kevin, Pattanaik, Sumanta, University of Central Florida
-
Abstract / Description
-
Rendering of natural scenes has interested the scientific community for a long time due to its numerous applications. The targeted goal is to create images that are similar to what a viewer can see in real life with his/her eyes. The main obstacle is complexity: nature scenes from real life contain a huge number of small details that are hard to model, take a lot of time to render and require a huge amount of memory unavailable in current computers. This complexity mainly comes from geometry...
Show moreRendering of natural scenes has interested the scientific community for a long time due to its numerous applications. The targeted goal is to create images that are similar to what a viewer can see in real life with his/her eyes. The main obstacle is complexity: nature scenes from real life contain a huge number of small details that are hard to model, take a lot of time to render and require a huge amount of memory unavailable in current computers. This complexity mainly comes from geometry and lighting. The goal of our research is to overcome this complexity and to achieve real-time rendering of nature scenes while providing visually convincing dynamic global illumination. Our work focuses on grass and trees as they are commonly visible in everyday life. We handle geometry and lighting complexities for grass to render millions of grass blades interactively with dynamic lighting. As for lighting complexity, we address real-time rendering of trees by proposing a lighting model that handles indirect lighting. Our work makes extensive use of the current generation of Graphics Processing Units (GPUs) to meet the real-time requirement and to leave the CPU free to carry out other tasks.
Show less
-
Date Issued
-
2008
-
Identifier
-
CFE0002262, ucf:47868
-
Format
-
Document (PDF)
-
PURL
-
http://purl.flvc.org/ucf/fd/CFE0002262
-
-
Title
-
COMPREHENDING SYNTHETIC SPEECH: PERSONAL AND PRODUCTION INFLUENCES.
-
Creator
-
Wang Costello, Jingjing, Gilson, Richard, University of Central Florida
-
Abstract / Description
-
With the increasing prevalence of voice-production technology across societies, clear comprehension while listening to synthetic speech is an obvious goal. Common human factors influences include the listener's language familiarity and age. Production factors include the speaking rate and clarity. This study investigated the speaking comprehension performance of younger and older adults who learned English as their first or second language. Presentations varied by the rate of delivery in...
Show moreWith the increasing prevalence of voice-production technology across societies, clear comprehension while listening to synthetic speech is an obvious goal. Common human factors influences include the listener's language familiarity and age. Production factors include the speaking rate and clarity. This study investigated the speaking comprehension performance of younger and older adults who learned English as their first or second language. Presentations varied by the rate of delivery in words per minute (wpm) and in two forms, synthetic or natural speech. The results showed that younger adults had significantly higher comprehension performance than older adults. English as First Language (EFL) participants performed better than English as Second Language (ESL) participants for both younger and older adults, although the performance gap for the older adults was significantly larger than for younger adults. Younger adults performed significantly better than older adults at the slow speech rate (127 wpm), but surprisingly at the medium speech rate (188 wpm), both age groups performed similarly. Both young and older participants had better comprehension when listening to synthetic speech than natural speech. Both theoretical and design implications are provided from these findings. A cognitive diagnostic tool is proposed as a recommendation for future research.
Show less
-
Date Issued
-
2011
-
Identifier
-
CFE0003925, ucf:48703
-
Format
-
Document (PDF)
-
PURL
-
http://purl.flvc.org/ucf/fd/CFE0003925
-
-
Title
-
THE ACQUISITION OF LEXICAL KNOWLEDGE FROM THE WEB FOR ASPECTS OF SEMANTIC INTERPRETATION.
-
Creator
-
Schwartz, Hansen, Gomez, Fernando, University of Central Florida
-
Abstract / Description
-
This work investigates the effective acquisition of lexical knowledge from the Web to perform semantic interpretation. The Web provides an unprecedented amount of natural language from which to gain knowledge useful for semantic interpretation. The knowledge acquired is described as common sense knowledge, information one uses in his or her daily life to understand language and perception. Novel approaches are presented for both the acquisition of this knowledge and use of the knowledge in...
Show moreThis work investigates the effective acquisition of lexical knowledge from the Web to perform semantic interpretation. The Web provides an unprecedented amount of natural language from which to gain knowledge useful for semantic interpretation. The knowledge acquired is described as common sense knowledge, information one uses in his or her daily life to understand language and perception. Novel approaches are presented for both the acquisition of this knowledge and use of the knowledge in semantic interpretation algorithms. The goal is to increase accuracy over other automatic semantic interpretation systems, and in turn enable stronger real world applications such as machine translation, advanced Web search, sentiment analysis, and question answering. The major contributions of this dissertation consist of two methods of acquiring lexical knowledge from the Web, namely a database of common sense knowledge and Web selectors. The first method is a framework for acquiring a database of concept relationships. To acquire this knowledge, relationships between nouns are found on the Web and analyzed over WordNet using information-theory, producing information about concepts rather than ambiguous words. For the second contribution, words called Web selectors are retrieved which take the place of an instance of a target word in its local context. The selectors serve for the system to learn the types of concepts that the sense of a target word should be similar. Web selectors are acquired dynamically as part of a semantic interpretation algorithm, while the relationships in the database are useful to stand-alone programs. A final contribution of this dissertation concerns a novel semantic similarity measure and an evaluation of similarity and relatedness measures on tasks of concept similarity. Such tasks are useful when applying acquired knowledge to semantic interpretation. Applications to word sense disambiguation, an aspect of semantic interpretation, are used to evaluate the contributions. Disambiguation systems which utilize semantically annotated training data are considered supervised. The algorithms of this dissertation are considered minimally-supervised; they do not require training data created by humans, though they may use human-created data sources. In the case of evaluating a database of common sense knowledge, integrating the knowledge into an existing minimally-supervised disambiguation system significantly improved results -- a 20.5\% error reduction. Similarly, the Web selectors disambiguation system, which acquires knowledge directly as part of the algorithm, achieved results comparable with top minimally-supervised systems, an F-score of 80.2\% on a standard noun disambiguation task. This work enables the study of many subsequent related tasks for improving semantic interpretation and its application to real-world technologies. Other aspects of semantic interpretation, such as semantic role labeling could utilize the same methods presented here for word sense disambiguation. As the Web continues to grow, the capabilities of the systems in this dissertation are expected to increase. Although the Web selectors system achieves great results, a study in this dissertation shows likely improvements from acquiring more data. Furthermore, the methods for acquiring a database of common sense knowledge could be applied in a more exhaustive fashion for other types of common sense knowledge. Finally, perhaps the greatest benefits from this work will come from the enabling of real world technologies that utilize semantic interpretation.
Show less
-
Date Issued
-
2011
-
Identifier
-
CFE0003688, ucf:48805
-
Format
-
Document (PDF)
-
PURL
-
http://purl.flvc.org/ucf/fd/CFE0003688
-
-
Title
-
Development of Cytotoxic Natural Killer Cells for Ovarian Cancer Treatment.
-
Creator
-
Pandey, Veethika, Altomare, Deborah, Zhao, Jihe, Khaled, Annette, Estevez, Alvaro, University of Central Florida
-
Abstract / Description
-
Ovarian cancer is a leading cause of gynecological malignancy. Cytoreductive surgery and frontline platinum/taxane-based chemotherapy provides good initial efficacy in the treatment, but poor long-term patient survival. This is mainly caused by tumor relapse due to intraperitoneal spreading and ineffective alternate therapies to treat these resistant tumors. The challenge in the field is to develop strategies that would prove effective in these patients and extend overall survival.Over the...
Show moreOvarian cancer is a leading cause of gynecological malignancy. Cytoreductive surgery and frontline platinum/taxane-based chemotherapy provides good initial efficacy in the treatment, but poor long-term patient survival. This is mainly caused by tumor relapse due to intraperitoneal spreading and ineffective alternate therapies to treat these resistant tumors. The challenge in the field is to develop strategies that would prove effective in these patients and extend overall survival.Over the years, various treatments have been developed for the treatment of cancer amongst which, adoptive cell immunotherapy has shown promising results. But despite the efficacy seen in the clinic, there are concerns with the complexity of treatment and associated side effects. Therefore, there is still a need for better understanding of how different components of the immune system react to the presence of tumor. In this study, healthy human peripheral blood mononuclear cells (PBMCs) were used to examine the immune response in a mouse model with residual human ovarian tumor, where natural killer (NK) cells were found to be the effector cells that elicited an anti-tumor response. Presence of tumor was found to stimulate NK cell expansion and cytotoxicity in mice treated intraperitoneally (IP) with PBMCs+Interleukin-2 (IL- 2). Intravenous (IV) adoptive transfer of isolated NK cells has been attempted in ovarian cancer patients before, but showed lack of persistence in patients resulting in lack of anti-tumor efficacy. Experiments in this study highlight the significance of NK cell-cytotoxic response to tumor, which may be attributed to interacting immune cell types in the PBMC population (when treated IP), as opposed to clinically used isolated NK cells showing lack of anti-tumor efficacy in ovarian cancer patients (when treated IV).iiiNK cell immunotherapy is mainly limited by insufficient numbers generated for adoptive transfer, limited in vivo life span after adoptive transfer, lack of cytotoxicity and some logistical concerns that impede its widespread implementation. Therefore there is a need to develop methods of NK cell expansion that provide stimulation similar to other immune cell types in the PBMC population. The second part of this study utilizes a method of in vivo NK cell expansion using a particle-based approach in which plasma membranes of K562-MB21-41BBL cells (K562 cells expressing membrane-bound IL-21 and 41BB ligand) are used for specific NK cell expansion from PBMCs. NK cells expanded with this method were cytotoxic, showed in vivo persistence and biodistribution in different organs.Collectively, these studies show that NK cells are a major innate immune component that can recognize and kill the tumor. Their cytotoxic ability, using particle-based stimulation, can be enhanced for a second-line treatment of relapsed tumors such as in ovarian cancer as well as other cancer types.
Show less
-
Date Issued
-
2015
-
Identifier
-
CFE0006369, ucf:51531
-
Format
-
Document (PDF)
-
PURL
-
http://purl.flvc.org/ucf/fd/CFE0006369
-
-
Title
-
Resource allocation and load-shedding policies based on Markov decision processes for renewable energy generation and storage.
-
Creator
-
Jimenez, Edwards, Atia, George, Richie, Samuel, Pazour, Jennifer, University of Central Florida
-
Abstract / Description
-
In modern power systems, renewable energy has become an increasingly popular form of energy generation as a result of all the rules and regulations that are being implemented towards achieving clean energy worldwide. However, clean energy can have drawbacks in several forms. Wind energy, for example can introduce intermittency. In this thesis, we discuss a method to deal with this intermittency. In particular, by shedding some specific amount of load we can avoid a total system breakdown of...
Show moreIn modern power systems, renewable energy has become an increasingly popular form of energy generation as a result of all the rules and regulations that are being implemented towards achieving clean energy worldwide. However, clean energy can have drawbacks in several forms. Wind energy, for example can introduce intermittency. In this thesis, we discuss a method to deal with this intermittency. In particular, by shedding some specific amount of load we can avoid a total system breakdown of the entire power plant. The load shedding method discussed in this thesis utilizes a Markov Decision Process with backward policy iteration. This is based on a probabilistic method that chooses the best load-shedding path that minimizes the expected total cost to ensure no power failure. We compare our results with two control policies, a load-balancing policy and a less-load shedding policy. It is shown that the proposed MDP policy outperforms the other control policies and achieves the minimum total expected cost.
Show less
-
Date Issued
-
2015
-
Identifier
-
CFE0005635, ucf:50222
-
Format
-
Document (PDF)
-
PURL
-
http://purl.flvc.org/ucf/fd/CFE0005635
-
-
Title
-
Automatic 3D human modeling: an initial stage towards 2-way inside interaction in mixed reality.
-
Creator
-
Xiong, Yiyan, Hughes, Charles, Pattanaik, Sumanta, Laviola II, Joseph, Moshell, Michael, University of Central Florida
-
Abstract / Description
-
3D human models play an important role in computer graphics applications from a wide range of domains, including education, entertainment, medical care simulation and military training. In many situations, we want the 3D model to have a visual appearance that matches that of a specific living person and to be able to be controlled by that person in a natural manner. Among other uses, this approach supports the notion of human surrogacy, where the virtual counterpart provides a remote presence...
Show more3D human models play an important role in computer graphics applications from a wide range of domains, including education, entertainment, medical care simulation and military training. In many situations, we want the 3D model to have a visual appearance that matches that of a specific living person and to be able to be controlled by that person in a natural manner. Among other uses, this approach supports the notion of human surrogacy, where the virtual counterpart provides a remote presence for the human who controls the virtual character's behavior. In this dissertation, a human modeling pipeline is proposed for the problem of creating a 3D digital model of a real person. Our solution involves reshaping a 3D human template with a 2D contour of the participant and then mapping the captured texture of that person to the generated mesh. Our method produces an initial contour of a participant by extracting the user image from a natural background. One particularly novel contribution in our approach is the manner in which we improve the initial vertex estimate. We do so through a variant of the ShortStraw corner-finding algorithm commonly used in sketch-based systems. Here, we develop improvements to ShortStraw, presenting an algorithm called IStraw, and then introduce adaptations of this improved version to create a corner-based contour segmentatiuon algorithm. This algorithm provides significant improvements on contour matching over previously developed systems, and does so with low computational complexity. The system presented here advances the state of the art in the following aspects. First, the human modeling process is triggered automatically by matching the participant's pose with an initial pose through a tracking device and software. In our case, the pose capture and skeletal model are provided by the Microsoft Kinect and its associated SDK. Second, color image, depth data, and human tracking information from the Kinect and its SDK are used to automatically extract the contour of the participant and then generate a 3D human model with skeleton. Third, using the pose and the skeletal model, we segment the contour into eight parts and then match the contour points on each segment to a corresponding anchor set associated with a 3D human template. Finally, we map the color image of the person to the 3D model as its corresponding texture map. The whole modeling process only take several seconds and the resulting human model looks like the real person. The geometry of the 3D model matches the contour of the real person, and the model has a photorealistic texture. Furthermore, the mesh of the human model is attached to the skeleton provided in the template, so the model can support programmed animations or be controlled by real people. This human control is commonly done through a literal mapping (motion capture) or a gesture-based puppetry system. Our ultimate goal is to create a mixed reality (MR) system, in which the participants can manipulate virtual objects, and in which these virtual objects can affect the participant, e.g., by restricting theirmobility. This MR system prototype design motivated the work of this dissertation, since a realistic 3D human model of the participant is an essential part of implementing this vision.
Show less
-
Date Issued
-
2014
-
Identifier
-
CFE0005277, ucf:50543
-
Format
-
Document (PDF)
-
PURL
-
http://purl.flvc.org/ucf/fd/CFE0005277
-
-
Title
-
ON RIGHTS: A DEFENSE AND ANALYSIS OF RIGHTS THROUGH NATURAL LAW.
-
Creator
-
Lopez, Ramon, Kiel, Dwight, University of Central Florida
-
Abstract / Description
-
One of the central questions in political theory deals with the nature of rights. What sorts of rights do people possess? How are these rights justified? How ought these rights be reflected and related when seen in political, economic, and social institutions? Following the publication of John Rawls' A Theory of Justice (1971) and Robert Nozick's Anarchy, State, and Utopia (1974), rights have once again returned to dominate much of contemporary political theory. However, natural law, which...
Show moreOne of the central questions in political theory deals with the nature of rights. What sorts of rights do people possess? How are these rights justified? How ought these rights be reflected and related when seen in political, economic, and social institutions? Following the publication of John Rawls' A Theory of Justice (1971) and Robert Nozick's Anarchy, State, and Utopia (1974), rights have once again returned to dominate much of contemporary political theory. However, natural law, which was the historical basis of the early Enlightenment theories of rights, is no longer the primary system appealed to when discussing rights. In fact, classical natural law has been all but discarded in most of political theory today. There has also been renewed debate over the nature of public neutrality, and what the relationship ought to be between the public and private sphere. The mainstream view of how our liberties relate to our rights, as well as what kinds of rights we have over our private affairs, has come under fire from a newly emerging political philosophy known as communitarianism. This thesis will present a robust theory of rights that provides a new understanding of the relationship between positive and negative rights through a defense of classical natural law as an ethical foundation for political theory. It will side with the communitarian critics of public neutrality, and offer a practical method of determining when the state is justified in limiting private liberties due to public interest.
Show less
-
Date Issued
-
2011
-
Identifier
-
CFH0003856, ucf:44695
-
Format
-
Document (PDF)
-
PURL
-
http://purl.flvc.org/ucf/fd/CFH0003856
-
-
Title
-
THE EFFECTS OF AUDITORY STIMULI ON STRESS LEVELS OF ADULT PATIENTS IN THE CRITICAL CARE SETTING.
-
Creator
-
Ellermets, Jessica, Heglund, Stephen, University of Central Florida
-
Abstract / Description
-
The purpose of this review of literature is to explore the effects of interventional and environmental auditory stimuli on the adult critical care population. Current research has yet to compare and contrast the effectiveness of various interventional auditory stimuli on stress relief, an oversight this thesis aims to remedy. Modern day critical care settings demand the identification of the most therapeutic interventional auditory stimulus and the most stress-inducing environmental stimuli,...
Show moreThe purpose of this review of literature is to explore the effects of interventional and environmental auditory stimuli on the adult critical care population. Current research has yet to compare and contrast the effectiveness of various interventional auditory stimuli on stress relief, an oversight this thesis aims to remedy. Modern day critical care settings demand the identification of the most therapeutic interventional auditory stimulus and the most stress-inducing environmental stimuli, so that interventions can be made to optimize patient stress levels and improve outcomes. Suggestions will be made on how to simultaneously reduce harmful or stress inducing auditory stimuli in the critical care setting and implement the optimal stress-relieving interventional auditory stimuli.
Show less
-
Date Issued
-
2015
-
Identifier
-
CFH0004853, ucf:45482
-
Format
-
Document (PDF)
-
PURL
-
http://purl.flvc.org/ucf/fd/CFH0004853
Pages