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PHARMACOGENOMIC MANAGEMENT OF FAMILIAL HYPERCHOLESTEROLEMIA: AN INTEGRATIVE REVIEW OF THE LITERATURE
- Date Issued:
- 2016
- Abstract/Description:
- The purpose of this thesis is to examine familial hypercholesterolemia (FH) and emerging pharmacogenomics therapies that propose to lower serum low density lipid (LDL) levels. The search of various data bases resulted in nine research articles being selected for review. Syntheses of the articles suggest emerging phamacogenomic drug therapy can improve treatment outcomes for individuals with a diagnosis of FH. The Human Genome Project (HGP) has had far reaching applications for genomic technologies and pharmacagenomic interventions, tailored to human conditions associated with select genomic traits. Synthesis of nine research articles demonstrate that little is known on the topic and reveals extensive gaps in the evidence. This thesis concludes with implications for nursing education, practice, policy and research along with limitations are noted.
Title: | PHARMACOGENOMIC MANAGEMENT OF FAMILIAL HYPERCHOLESTEROLEMIA: AN INTEGRATIVE REVIEW OF THE LITERATURE. |
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Name(s): |
Skibo, Brian V., Author Bushy, Angeline, Committee Chair Kubiet, Leslee, Committee Member University of Central Florida, Degree Grantor |
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Type of Resource: | text | |
Date Issued: | 2016 | |
Publisher: | University of Central Florida | |
Language(s): | Engilsh | |
Abstract/Description: | The purpose of this thesis is to examine familial hypercholesterolemia (FH) and emerging pharmacogenomics therapies that propose to lower serum low density lipid (LDL) levels. The search of various data bases resulted in nine research articles being selected for review. Syntheses of the articles suggest emerging phamacogenomic drug therapy can improve treatment outcomes for individuals with a diagnosis of FH. The Human Genome Project (HGP) has had far reaching applications for genomic technologies and pharmacagenomic interventions, tailored to human conditions associated with select genomic traits. Synthesis of nine research articles demonstrate that little is known on the topic and reveals extensive gaps in the evidence. This thesis concludes with implications for nursing education, practice, policy and research along with limitations are noted. | |
Identifier: | CFH2000076 (IID), ucf:45544 (fedora) | |
Note(s): |
2016-08-01 B.S.N. College of Nursing, Bachelors This record was generated from author submitted information. |
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Subject(s): |
Pharmacogenomics Hypercholesterolemia personalized medicine genetics genomics nursing |
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Persistent Link to This Record: | http://purl.flvc.org/ucf/fd/CFH2000076 | |
Restrictions on Access: | public | |
Host Institution: | UCF |