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PHARMACOGENOMIC MANAGEMENT OF FAMILIAL HYPERCHOLESTEROLEMIA: AN INTEGRATIVE REVIEW OF THE LITERATURE

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Date Issued:
2016
Abstract/Description:
The purpose of this thesis is to examine familial hypercholesterolemia (FH) and emerging pharmacogenomics therapies that propose to lower serum low density lipid (LDL) levels. The search of various data bases resulted in nine research articles being selected for review. Syntheses of the articles suggest emerging phamacogenomic drug therapy can improve treatment outcomes for individuals with a diagnosis of FH. The Human Genome Project (HGP) has had far reaching applications for genomic technologies and pharmacagenomic interventions, tailored to human conditions associated with select genomic traits. Synthesis of nine research articles demonstrate that little is known on the topic and reveals extensive gaps in the evidence. This thesis concludes with implications for nursing education, practice, policy and research along with limitations are noted.
Title: PHARMACOGENOMIC MANAGEMENT OF FAMILIAL HYPERCHOLESTEROLEMIA: AN INTEGRATIVE REVIEW OF THE LITERATURE.
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Name(s): Skibo, Brian V., Author
Bushy, Angeline, Committee Chair
Kubiet, Leslee, Committee Member
University of Central Florida, Degree Grantor
Type of Resource: text
Date Issued: 2016
Publisher: University of Central Florida
Language(s): Engilsh
Abstract/Description: The purpose of this thesis is to examine familial hypercholesterolemia (FH) and emerging pharmacogenomics therapies that propose to lower serum low density lipid (LDL) levels. The search of various data bases resulted in nine research articles being selected for review. Syntheses of the articles suggest emerging phamacogenomic drug therapy can improve treatment outcomes for individuals with a diagnosis of FH. The Human Genome Project (HGP) has had far reaching applications for genomic technologies and pharmacagenomic interventions, tailored to human conditions associated with select genomic traits. Synthesis of nine research articles demonstrate that little is known on the topic and reveals extensive gaps in the evidence. This thesis concludes with implications for nursing education, practice, policy and research along with limitations are noted.
Identifier: CFH2000076 (IID), ucf:45544 (fedora)
Note(s): 2016-08-01
B.S.N.
College of Nursing,
Bachelors
This record was generated from author submitted information.
Subject(s): Pharmacogenomics
Hypercholesterolemia
personalized medicine
genetics
genomics
nursing
Persistent Link to This Record: http://purl.flvc.org/ucf/fd/CFH2000076
Restrictions on Access: public
Host Institution: UCF

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