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EXPLORATION OF BIOACTIVE COMPOUNDS OF GINGER AS A FOLK REMEDY FOR MIGRAINES

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Date Issued:
2017
Abstract/Description:
Ginger (Zingiber Officinale) has been used in Asia for centuries to treat various ailments. Ginger has been reported to alleviate migraine pain via four bioactive compounds that can reduce nitric oxide synthase (NOS) resulting in the inhibition of nitric oxide (NO). The inhibition of nitric oxide results in the vasoconstriction of the intracranial blood vessels alleviating migraine pain. It is hypothesized that ginger has structural similarities to vasoconstrictor drugs causing similar receptor interactions. A review of the bioactive compounds in ginger and popular vasoconstrictor drugs was done to determine structural similarities. The results of this study show that the compounds in ginger share no structural similarities with vasoconstrictor drugs used in the treatment of migraine headaches.
Title: EXPLORATION OF BIOACTIVE COMPOUNDS OF GINGER AS A FOLK REMEDY FOR MIGRAINES.
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Name(s): Aleger, Nathan Vorbes, Author
Elsheimer, Seth, Committee Chair
Samsam, Mohtashem, Committee Member
University of Central Florida, Degree Grantor
Type of Resource: text
Date Issued: 2017
Publisher: University of Central Florida
Language(s): English
Abstract/Description: Ginger (Zingiber Officinale) has been used in Asia for centuries to treat various ailments. Ginger has been reported to alleviate migraine pain via four bioactive compounds that can reduce nitric oxide synthase (NOS) resulting in the inhibition of nitric oxide (NO). The inhibition of nitric oxide results in the vasoconstriction of the intracranial blood vessels alleviating migraine pain. It is hypothesized that ginger has structural similarities to vasoconstrictor drugs causing similar receptor interactions. A review of the bioactive compounds in ginger and popular vasoconstrictor drugs was done to determine structural similarities. The results of this study show that the compounds in ginger share no structural similarities with vasoconstrictor drugs used in the treatment of migraine headaches.
Identifier: CFH2000251 (IID), ucf:45962 (fedora)
Note(s): 2017-12-01
B.S.
College of Sciences, Chemistry
Bachelors
This record was generated from author submitted information.
Subject(s): Ginger
migraines
nitric oxide
vasoconstriction
Persistent Link to This Record: http://purl.flvc.org/ucf/fd/CFH2000251
Restrictions on Access: public
Host Institution: UCF

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