You are here

NON-ACUTE COGNITIVE SEQUELAE ASSOCIATED WITH RECREATIONAL ECSTASY USE: A META-ANALYSIS

Download pdf | Full Screen View

Date Issued:
2005
Abstract/Description:
Studies using animal models have found considerable evidence of neurological damage resulting from exposure to 3,4- methylenedioxymethamphetamine (MDMA, ecstasy). Yet, studies comparing the cognitive performance of human recreational ecstasy users to ecstasy naïve controls have produced inconsistent results. The present study is a meta-analysis of the published empirical literature on the cognitive sequelae of human recreational ecstasy use. The pooled effect size estimate for combined cognitive domains was statistically significant and moderate in size. Small to large, statistically significant aggregate effect sizes resulted for eight of the nine cognitive ability domains included in the analysis. Moderator analyses suggested that frequent ecstasy use is associated with greater cognitive impairment, cognitive impairment can occur after relatively low amounts of total lifetime cumulative use, and recovery of functioning does not occur within one year post cessation.
Title: NON-ACUTE COGNITIVE SEQUELAE ASSOCIATED WITH RECREATIONAL ECSTASY USE: A META-ANALYSIS.
21 views
12 downloads
Name(s): Linkovich Kyle, Tiffany, Author
Dunn, Michael, Committee Chair
University of Central Florida, Degree Grantor
Type of Resource: text
Date Issued: 2005
Publisher: University of Central Florida
Language(s): English
Abstract/Description: Studies using animal models have found considerable evidence of neurological damage resulting from exposure to 3,4- methylenedioxymethamphetamine (MDMA, ecstasy). Yet, studies comparing the cognitive performance of human recreational ecstasy users to ecstasy naïve controls have produced inconsistent results. The present study is a meta-analysis of the published empirical literature on the cognitive sequelae of human recreational ecstasy use. The pooled effect size estimate for combined cognitive domains was statistically significant and moderate in size. Small to large, statistically significant aggregate effect sizes resulted for eight of the nine cognitive ability domains included in the analysis. Moderator analyses suggested that frequent ecstasy use is associated with greater cognitive impairment, cognitive impairment can occur after relatively low amounts of total lifetime cumulative use, and recovery of functioning does not occur within one year post cessation.
Identifier: CFE0000701 (IID), ucf:46614 (fedora)
Note(s): 2005-08-01
Ph.D.
Arts and Sciences, Department of Psychology
Doctorate
This record was generated from author submitted information.
Subject(s): meta-analysis
MDMA
ecstasy
cognitive functioning
Persistent Link to This Record: http://purl.flvc.org/ucf/fd/CFE0000701
Restrictions on Access: campus 2008-01-31
Host Institution: UCF

In Collections