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Posttraumatic Stress Disorder or Combat Experience? A Functional Near-infrared Spectroscopy Study of Trauma-related Auditory and Olfactory Cues

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Date Issued:
2017
Abstract/Description:
While the clinical communities are aware of the prevalence of posttraumatic stress disorder (PTSD) among OEF/OIF/OND veterans, further efforts are necessary to bolster comprehensive strategies for assessment and treatment. The purpose of this study was to investigate whether a combat-related PTSD symptom provocation paradigm would elicit unique neurological responses via functional near-infrared spectroscopy across three groups (-) combat veterans with PTSD, combat veterans without PTSD, and nonmilitary participants without PTSD. Results indicated that combat veterans with PTSD demonstrated significant activation during exposure to a trauma-related sound compared to nonmilitary personnel at channels 14 (d = 1.03) and 15 (d = 1.30) and combat veterans without PTSD at channel 14 (d = 0.87). Specifically, this increased neural activation was approximately located in the right superior/medial prefrontal cortex (BA 9/10), associated with evaluating cue-familiarity and emotional detachment. Results were less clear with respect to a combat-related odor. These results suggest a specific neurophysiological response to trauma-related cues and if replicated, may offer a biomarker for combat-related PTSD. Such a response could provide incremental validity over diagnostic assessments alone and assist in planning and monitoring of treatment outcome.
Title: Posttraumatic Stress Disorder or Combat Experience? A Functional Near-infrared Spectroscopy Study of Trauma-related Auditory and Olfactory Cues.
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Name(s): Gramlich, Michael, Author
Neer, Sandra, Committee Chair
Bowers, Clint, Committee Member
Beidel, Deborah, Committee Member
University of Central Florida, Degree Grantor
Type of Resource: text
Date Issued: 2017
Publisher: University of Central Florida
Language(s): English
Abstract/Description: While the clinical communities are aware of the prevalence of posttraumatic stress disorder (PTSD) among OEF/OIF/OND veterans, further efforts are necessary to bolster comprehensive strategies for assessment and treatment. The purpose of this study was to investigate whether a combat-related PTSD symptom provocation paradigm would elicit unique neurological responses via functional near-infrared spectroscopy across three groups (-) combat veterans with PTSD, combat veterans without PTSD, and nonmilitary participants without PTSD. Results indicated that combat veterans with PTSD demonstrated significant activation during exposure to a trauma-related sound compared to nonmilitary personnel at channels 14 (d = 1.03) and 15 (d = 1.30) and combat veterans without PTSD at channel 14 (d = 0.87). Specifically, this increased neural activation was approximately located in the right superior/medial prefrontal cortex (BA 9/10), associated with evaluating cue-familiarity and emotional detachment. Results were less clear with respect to a combat-related odor. These results suggest a specific neurophysiological response to trauma-related cues and if replicated, may offer a biomarker for combat-related PTSD. Such a response could provide incremental validity over diagnostic assessments alone and assist in planning and monitoring of treatment outcome.
Identifier: CFE0006596 (IID), ucf:51297 (fedora)
Note(s): 2017-05-01
M.S.
Sciences, Psychology
Masters
This record was generated from author submitted information.
Subject(s): PTSD -- fNIRS -- combat veteran -- symptom provocation -- olfaction
Persistent Link to This Record: http://purl.flvc.org/ucf/fd/CFE0006596
Restrictions on Access: public 2017-05-15
Host Institution: UCF

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