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Fluid Dynamics Modeling and Sound Analysis of a Bileaflet Mechanical Heart Valve

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Date Issued:
2018
Abstract/Description:
Cardiovascular disease (CVD) is one of the main causes of death in the world. Some CVD involve severe heart valve disease that require valve replacement. There are more than 300,000 heart valves implanted worldwide, and about 85,000 heart valve replacements in the US. Approximately half of these valves are mechanical. Artificial valves may dysfunction leading to adverse hemodynamic conditions. Understanding the normal and abnormal valve function is important as it help improve valve designs. Modeling of heart valve hemodynamics using computational fluid dynamics (CFD) provides a comprehensive analysis of flow, which can potentially help explain clinical observations and support therapeutic decision-making. This detailed information might not be accessible with in-vivo measurements. On the other hand, finite element analysis (FEA), is an efficient way to analyze the interactions of blood flow with blood vessel and tissue layers. In this project both CFD and FEA simulations were performed to investigate the flow-induced sound generation and propagation of sound waves through a tissue-like material. This method is based on mapping the transient pressure (force) fluctuations on the vessel wall and solving for the structural vibrations in the frequency domain. These vibrations would then be detected as sound on the epidermal surface. Advantages of the methods used in the current study include: (a) capability of providing accurate solution with a faster solution time; (b) inclusion of the fluid(-)structure interaction between blood flow and the arterial wall; and (c) accurately capturing some of the spectral features of the velocity fluctuation measured over the epidermal surface.
Title: Fluid Dynamics Modeling and Sound Analysis of a Bileaflet Mechanical Heart Valve.
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Name(s): Khalili, Fardin, Author
Mansy, Hansen, Committee Chair
Kassab, Alain, Committee Member
Steward, Robert, Committee Member
Zaurin, Ricardo, Committee Member
University of Central Florida, Degree Grantor
Type of Resource: text
Date Issued: 2018
Publisher: University of Central Florida
Language(s): English
Abstract/Description: Cardiovascular disease (CVD) is one of the main causes of death in the world. Some CVD involve severe heart valve disease that require valve replacement. There are more than 300,000 heart valves implanted worldwide, and about 85,000 heart valve replacements in the US. Approximately half of these valves are mechanical. Artificial valves may dysfunction leading to adverse hemodynamic conditions. Understanding the normal and abnormal valve function is important as it help improve valve designs. Modeling of heart valve hemodynamics using computational fluid dynamics (CFD) provides a comprehensive analysis of flow, which can potentially help explain clinical observations and support therapeutic decision-making. This detailed information might not be accessible with in-vivo measurements. On the other hand, finite element analysis (FEA), is an efficient way to analyze the interactions of blood flow with blood vessel and tissue layers. In this project both CFD and FEA simulations were performed to investigate the flow-induced sound generation and propagation of sound waves through a tissue-like material. This method is based on mapping the transient pressure (force) fluctuations on the vessel wall and solving for the structural vibrations in the frequency domain. These vibrations would then be detected as sound on the epidermal surface. Advantages of the methods used in the current study include: (a) capability of providing accurate solution with a faster solution time; (b) inclusion of the fluid(-)structure interaction between blood flow and the arterial wall; and (c) accurately capturing some of the spectral features of the velocity fluctuation measured over the epidermal surface.
Identifier: CFE0007029 (IID), ucf:52038 (fedora)
Note(s): 2018-05-01
Ph.D.
Engineering and Computer Science, Mechanical and Aerospace Engineering
Doctoral
This record was generated from author submitted information.
Subject(s): Bileaflet mechanical heart valve
computational fluid dynamics (CFD)
finite element methods (FEM)
Turbulence
cardiovascular disease
hemodynamics
hemoacoustics
Persistent Link to This Record: http://purl.flvc.org/ucf/fd/CFE0007029
Restrictions on Access: public 2018-05-15
Host Institution: UCF

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