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Antibodies to milk antigens in human coronary heart disease
| Title: | Antibodies to milk antigens in human coronary heart disease. |
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| Name(s): |
Spinos, Efstathios, Author Sweeney, Michael J., Committee Chair Natural Sciences, Degree Grantor |
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| Type of Resource: | text | |
| Date Issued: | 1977 | |
| Publisher: | Florida Technical University | |
| Language(s): | English | |
| Abstract/Description: | Florida Technological University College of Natural Sciences Thesis; Milk protein has been implicated as a factor in the development of atherosclerosis. Significantly higher titers of antibodies (P < 0.0002) toward milk antigens were observed in patients suffering from coronary heart disease as compared to age matched controls. These hemagglutination titers were not sex related but may have been related to age. Specificity of the antigen-antibody reaction was demonstrated by a hemagglutination inhibition test. The complement fixation test was evaluated and was less sensitive than the tanned hemaggIutination test. Treatment with 2-mercapto-ethanol resulted in reduced hemagglutination titers, indicating that significant antibody activity may be due to IgM. A special application of the Combs test detected specific antibodies on the surface of tanned and coated RBC which did not otherwise produce detectable agglutination. | |
| Identifier: | CFR0003521 (IID), ucf:52985 (fedora) | |
| Note(s): |
1977-05-16 M.S. Biological Sciences Masters This record was generated from author submitted information. Electronically reproduced by the University of Central Florida from a book held in the John C. Hitt Library at the University of Central Florida, Orlando. |
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| Subject(s): |
Coronary heart disease Immunopathology Milk |
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| Persistent Link to This Record: | http://purl.flvc.org/ucf/fd/CFR0003521 | |
| Restrictions on Access: | public | |
| Host Institution: | UCF |
