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Re-examining subfamily classifications for the alu family of repeated dna sequences

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Date Issued:
1994
Abstract/Description:
University of Central Florida College of Arts and Sciences Thesis; The primate Alu family of repetitive elements has been widely characterized. This ubiquitous class of retroposons has been found to occupy some 5% of the human genome. This hetergenous group of Short Interspersed Nucleic acid Elements (SINEs) has been theorized to possess an identifiable subfamily structure between and within various taxonomic levels in primates. It has been postulated that humans possess up to 6 Alu sequences and found evidence supporting the amplification/fixation theory in 5 subfamilies. The research presented in this thesis posits that Quentin's method of alignment used in the correspondence analysis is questionable. A reexamination using an alternative, perhaps more tenable, alignment of the Alu sequences may allow for a more lucid and accurate identification of Alu subfamily structure in the human genome.
Title: Re-examining subfamily classifications for the alu family of repeated dna sequences.
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Name(s): York, William A., Author
Sweet, Haven C., Committee Chair
Arts and Sciences, Degree Grantor
Type of Resource: text
Date Issued: 1994
Publisher: University of Central Florida
Language(s): English
Abstract/Description: University of Central Florida College of Arts and Sciences Thesis; The primate Alu family of repetitive elements has been widely characterized. This ubiquitous class of retroposons has been found to occupy some 5% of the human genome. This hetergenous group of Short Interspersed Nucleic acid Elements (SINEs) has been theorized to possess an identifiable subfamily structure between and within various taxonomic levels in primates. It has been postulated that humans possess up to 6 Alu sequences and found evidence supporting the amplification/fixation theory in 5 subfamilies. The research presented in this thesis posits that Quentin's method of alignment used in the correspondence analysis is questionable. A reexamination using an alternative, perhaps more tenable, alignment of the Alu sequences may allow for a more lucid and accurate identification of Alu subfamily structure in the human genome.
Identifier: CFR0011936 (IID), ucf:53117 (fedora)
Note(s): 1994-12-01
M.S.
Biology
Masters
This record was generated from author submitted information.
Electronically reproduced by the University of Central Florida from a book held in the John C. Hitt Library at the University of Central Florida, Orlando.
Subject(s): Arts and Sciences -- Dissertations
Academic
Dissertations
Academic -- Arts and Sciences
Persistent Link to This Record: http://purl.flvc.org/ucf/fd/CFR0011936
Restrictions on Access: public
Host Institution: UCF

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