Current Search: McIntyre, Matthew (x)
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Title
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WHAT IS THE IMPORTANCE OF AGE AT MENARCHE ON ADULT HEIGHT RELATIVE TO OTHER KNOWN FACTORS?.
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Creator
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Kacerosky, Pamela, McIntyre, Matthew, University of Central Florida
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Abstract / Description
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Objectives: To analyze the association between age at menarche, as a measure of sexual maturation, and adult height from ten published studies. Methods: Compared published measurements of age at menarche, adult height, and within-sample relationships observed in ten studies, for women from several societies and socioeconomic backgrounds, living in the 20th century, Results: In these studies, early maturers were taller during pre-puberty, but had shorter adult height then later maturers. Late...
Show moreObjectives: To analyze the association between age at menarche, as a measure of sexual maturation, and adult height from ten published studies. Methods: Compared published measurements of age at menarche, adult height, and within-sample relationships observed in ten studies, for women from several societies and socioeconomic backgrounds, living in the 20th century, Results: In these studies, early maturers were taller during pre-puberty, but had shorter adult height then later maturers. Late maturers experience a longer period of pre-pubertal growth and a delayed age of peak height velocity, leading to an extended overall time of growth, until adult stature was obtained. Conclusions: Improved living conditions and energy balance increase childhood growth rate, and are associated with an earlier puberty, and shorter duration of growth. In developed countries duration of growth may play an increasingly important role in adult stature.
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Date Issued
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2011
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Identifier
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CFH0004090, ucf:44803
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Format
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Document (PDF)
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PURL
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http://purl.flvc.org/ucf/fd/CFH0004090
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Title
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THE ORIGINS OF LACTASE PERSISTENCE AND ONGOING CONVERGENT EVOLUTION.
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Creator
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Keller, Beth, McIntyre, Matthew, University of Central Florida
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Abstract / Description
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As a primary factor in human evolution, natural selection is an important component of genetic research. Studies of lactase persistence suggest that positive selection has played a powerful role in the adaptation to a lifelong consumption of fresh milk. Using multiple research studies of lactase persistence and suspected corresponding single nucleotide genetic polymorphisms, this study combines data sources to determine whether evidence exists for natural selection of a specific cytosine-to...
Show moreAs a primary factor in human evolution, natural selection is an important component of genetic research. Studies of lactase persistence suggest that positive selection has played a powerful role in the adaptation to a lifelong consumption of fresh milk. Using multiple research studies of lactase persistence and suspected corresponding single nucleotide genetic polymorphisms, this study combines data sources to determine whether evidence exists for natural selection of a specific cytosine-to-thymine genetic mutation located 13,910 base pairs (T-13910) upstream from the lactase gene. This polymorphism has potential to be a causal element for lactase persistence, and data suggest that natural selection has played a role in the rising frequency and distribution of this allele, if only in some regions. European and neighboring regions appear to have the highest frequencies with little or no frequency in Asia, Africa and Indonesia; however the presence of lactase persistence in those areas suggests convergent evolution may be occurring on a phenotypic level. To examine this possibility several other identified polymorphisms in the same region as the T-13910 will be included in this study.
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Date Issued
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2011
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Identifier
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CFE0003608, ucf:48890
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Format
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Document (PDF)
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PURL
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http://purl.flvc.org/ucf/fd/CFE0003608
