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- Title
- HUMAN PAPILLOMAVIRUS AND VACCINATION OF MALES: KNOWLEDGE, BELIEFS AND PERCEPTIONS OF REGISTERED NURSES.
- Creator
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White, Leah, Waldrop, Julee, University of Central Florida
- Abstract / Description
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Background: Human papillomavirus (HPV) infections are the most common sexually transmitted infections in the world today. HPV has been identified as the cause of both cancer and genital warts. A vaccine to prevent select types of HPV infection was developed and approved for males and females ages 9 to 26. This vaccine has not been universally accepted by healthcare providers, parents, or the public and has lower vaccination coverage rates than other recommended vaccines for the same age group...
Show moreBackground: Human papillomavirus (HPV) infections are the most common sexually transmitted infections in the world today. HPV has been identified as the cause of both cancer and genital warts. A vaccine to prevent select types of HPV infection was developed and approved for males and females ages 9 to 26. This vaccine has not been universally accepted by healthcare providers, parents, or the public and has lower vaccination coverage rates than other recommended vaccines for the same age group. Multiple studies addressing the knowledge, perceptions, and beliefs of providers and parents regarding the vaccine have taken place. Only a few studies with the nursing profession are found in the literature and they do not look at the vaccine in regards to males. Nurses are seen as one of the most trustworthy of professions. What nurses know, perceive and believe can impact both patients and those they come in contact with on an informal basis. Objective: The purpose of this study is to determine knowledge, beliefs, and perceptions of registered nurses about the human papillomavirus and associated vaccination for males. Methodology: This study took place in February of 2013 and used a descriptive correlational design with a cross-sectional survey. The survey was administered online to alumni of the University of Central Florida (UCF) College of Nursing, members of the Theta Epsilon chapter of Sigma Theta Tau International Honor Society, and current graduate nursing students and faculty of UCF College of Nursing. There were one hundred and twelve Registered Nurses that participated in the study. Findings: Knowledge of HPV varied among respondents. The vast majority knew that HPV was a common sexually transmitted infection however less were knowledgeable on specific iii information about the vaccine. Less than eighty percent of study participants knew that the vaccine was available for both males and females. Close to ninety percent of respondents agreed that vaccinating males would be important to protect their future partners from complications associated with HPV, such as genital warts and cervical cancer, and to protect themselves from future complications, such as genital warts and cancers. Participants with doctoral degrees possessed a significantly more favorable attitude (p<0.001) towards vaccine use in males than those with a bachelors degree. Conclusions: Nurses in this study were knowledgeable about specific HPV information but were less knowledgeable about the extent of infection seen in males or the availability of the vaccine for males. This study found inaccuracies and lack of knowledge among Registered Nurses that demonstrates the need for education about HPV and the associated vaccine. While the attitudes of the respondents reflect favorably toward the vaccine, there is still a need for education among this population.
Show less - Date Issued
- 2013
- Identifier
- CFH0004467, ucf:45128
- Format
- Document (PDF)
- PURL
- http://purl.flvc.org/ucf/fd/CFH0004467
- Title
- Zika virus-induced lysis of cervical cancer cells.
- Creator
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Krishnapura, Harini, Alexander, Kenneth, Parks, Griffith, Jewett, Mollie, University of Central Florida
- Abstract / Description
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Cervical cancer is the fourth most frequent cancer in women with an estimated 570,000 new cases globally in 2018. Treatment of advanced cervical cancer is often unsuccessful leading to high cancer-related mortality rates, especially in under-resourced countries. Recently, a possible role for the cell surface glycoprotein CD24 in host cell specificity of Zika virus was reported. As an extension of this work, Zika viruses have been proposed as oncolytic therapy for the treatment of...
Show moreCervical cancer is the fourth most frequent cancer in women with an estimated 570,000 new cases globally in 2018. Treatment of advanced cervical cancer is often unsuccessful leading to high cancer-related mortality rates, especially in under-resourced countries. Recently, a possible role for the cell surface glycoprotein CD24 in host cell specificity of Zika virus was reported. As an extension of this work, Zika viruses have been proposed as oncolytic therapy for the treatment of neuroblastoma and other CD24 positive tumors. To determine the permissiveness of cervical cancer cells to Zika virus infection and its association with CD24, we assessed cytopathic effect (CPE) induced by Zika virus in cervical cancer cell lines (HeLa, SiHa and CaSki) by light microscopy and by cytotoxicity assay. Cervical cancer cells were susceptible to Zika virus-induced apoptosis. Upon infection, the morphology of cervical cancer cells changed, exhibiting Zika virus-induced CPE. Cervical cancer cell expression of viral non-structural protein 1 (NS1) after infection demonstrated viral protein translation. Quantitative plaque assays demonstrated the production of competent virions. Because CD24 expression was found to be important for Zika virus infection in neuroblastoma cells, CD24 expression was assessed in cervical cancer cells. Cervical cancer cells expressed low but measurable levels of CD24 mRNA and protein. siRNA-mediated knockdown of CD24 resulted in reduced NS1 expression and reduced levels of virus-induced apoptosis. Taken together our data suggest a possible role for CD24 in Zika virus-induced apoptosis in cervical cancer cells. Zika virus-induced apoptosis of cultured cervical cancer cells presents the possibility for the use of Zika virus as a potential oncolytic therapy for cervical cancer.
Show less - Date Issued
- 2019
- Identifier
- CFE0007480, ucf:52682
- Format
- Document (PDF)
- PURL
- http://purl.flvc.org/ucf/fd/CFE0007480
- Title
- A Complex Calculus: How Message Format and Processing Route Coordinate to Influence HPV Vaccination Message Persuasiveness Among Young Adults.
- Creator
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Boutemen, Laura, Neuberger, Lindsay, Sellnow, Timothy, Miller, Ann, University of Central Florida
- Abstract / Description
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Human papillomavirus (HPV) infection may lead to cancer and genital warts yet can be prevented by a safe and effective vaccine recommended for individuals up to 26 years old. HPV vaccination rates remain low among college aged adults that represent a catch-up population still eligible to receive the HPV vaccine. This present study is a theory-based investigation employing the Heuristic Systematic Model to explore the effect of message format and processing route on attitude and behavioral...
Show moreHuman papillomavirus (HPV) infection may lead to cancer and genital warts yet can be prevented by a safe and effective vaccine recommended for individuals up to 26 years old. HPV vaccination rates remain low among college aged adults that represent a catch-up population still eligible to receive the HPV vaccine. This present study is a theory-based investigation employing the Heuristic Systematic Model to explore the effect of message format and processing route on attitude and behavioral intention in the context of HPV vaccination. Undergraduate students aged 17-26 years old (N = 261) from various majors (e.g., STEM, social sciences, humanities) participated in the study. An online message exposure experiment randomly assigned participants one of three messages in different message formats (i.e., accessible, scientific jargon, scientese) promoting HPV vaccination to examine the persuasive potential of clearly worded messages (i.e., accessible message), appropriately used scientific language (i.e., jargon message) and inappropriately used scientific terminology (i.e., scientese message) and the effect of processing route on attitude and behavioral intention pertaining to HPV vaccination. Additionally, the potential impact of scientific literacy was investigated. The three experimental conditions were compared to the control condition that corresponded to no message exposure. Quantitative data analyses revealed the scientese message was associated with higher intention to receive the HPV vaccine than the simply worded message among systematic processors only. Further, systematic processing was related to more favorable attitude toward the message and greater intention to obtain the vaccine. Findings of the current study can help inform future message development to design targeted persuasive messages aiming to encourage vaccination in an effort to augment HPV vaccination rates among the catch-up population.
Show less - Date Issued
- 2018
- Identifier
- CFE0006979, ucf:51658
- Format
- Document (PDF)
- PURL
- http://purl.flvc.org/ucf/fd/CFE0006979
- Title
- NARRATIVE BASED FEAR APPEALS: MANIPULATING GRAMMATICAL PERSON AND MESSAGE FRAME TO PROMOTE HPV AWARENESS AND RESPONSIBLE SEXUAL CONDUCT.
- Creator
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Spear, Jennifer, Miller, Ann, University of Central Florida
- Abstract / Description
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The utility of narrative as a persuasive mechanism has been increasingly investigated in recent years especially within the context of health behaviors. Although many studies have noted the effectiveness of narrative-based persuasive appeals, conceptual inconsistencies have made it difficult to determine what specific aspects of narrative messages lead to the most effective persuasive outcomes. In the present study, 145 female college students were randomly assigned to read one of four...
Show moreThe utility of narrative as a persuasive mechanism has been increasingly investigated in recent years especially within the context of health behaviors. Although many studies have noted the effectiveness of narrative-based persuasive appeals, conceptual inconsistencies have made it difficult to determine what specific aspects of narrative messages lead to the most effective persuasive outcomes. In the present study, 145 female college students were randomly assigned to read one of four narrative health messages about a female freshman college students experiences with the human papillomavirus (HPV). Two elements of the narrative message structure were manipulated: the message frame (gain framed vs. loss framed), and the grammatical person of the text (first-person vs. third-person).The messages were presented via the medium of an online blog. After reading a narrative participants responded to a brief questionnaire designed to measure perceptions of threat regarding HPV contraction, perceptions of efficacy regarding HPV prevention, and intentions to get the Gardasil vaccine. Participants exposed to loss framed messages reported higher levels of perceived threat (susceptibility and severity) than participants exposed to gain framed messages although participants in the gain framed message conditions reported higher levels of perceived self-efficacy. Significant correlations were also found between levels of reported character identification and the two threat variables. No effects were found for grammatical person.
Show less - Date Issued
- 2011
- Identifier
- CFE0003997, ucf:48673
- Format
- Document (PDF)
- PURL
- http://purl.flvc.org/ucf/fd/CFE0003997
- Title
- HAVE YOU HEARD? PREDICTORS OF HPV AWARENESS AMONG A RANDOM SAMPLE OF COLLEGE STUDENTS.
- Creator
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Arrastia, Meagan, Rivera, Fernando, University of Central Florida
- Abstract / Description
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College students have been identified as at high risk for contracting Human Papillomavirus (HPV) due to engaging in risky behaviors, such as binge drinking and unprotected sex. Before preventative measures like vaccination and condom usage can be promoted, awareness must be evaluated. A random sample of 438 college students was surveyed on their awareness of HPV using both paper and online surveying methods. Using binary logistic regression, HPV awareness was predicted using demographic...
Show moreCollege students have been identified as at high risk for contracting Human Papillomavirus (HPV) due to engaging in risky behaviors, such as binge drinking and unprotected sex. Before preventative measures like vaccination and condom usage can be promoted, awareness must be evaluated. A random sample of 438 college students was surveyed on their awareness of HPV using both paper and online surveying methods. Using binary logistic regression, HPV awareness was predicted using demographic measures. The majority of the sample reported having heard of HPV before. Sexually active respondents and females were significantly more likely to report awareness. Non-whites and first-generation college students were also more likely to report awareness. These demographic predictors will help identify groups needing educational and HPV intervention programs. Implications and further research is discussed.
Show less - Date Issued
- 2009
- Identifier
- CFE0002640, ucf:48208
- Format
- Document (PDF)
- PURL
- http://purl.flvc.org/ucf/fd/CFE0002640
- Title
- DEMAND STUDY FOR DENTAL HYGIENE BACHELOR DEGREE PROGRAM.
- Creator
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Driscoll, Annelise, Liberman, Aaron, University of Central Florida
- Abstract / Description
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The following is a study to determine if sufficient demand exists to start a Bachelor of Science and Master of Science degree program in dental hygiene through a joint agreement for completion degrees between Valencia Community College and the University of Central Florida. To accomplish this objective two survey instruments were administered to randomly selected licensed dentists and dental hygienists in the state of Florida. Dental hygienists represented the potential student base for the...
Show moreThe following is a study to determine if sufficient demand exists to start a Bachelor of Science and Master of Science degree program in dental hygiene through a joint agreement for completion degrees between Valencia Community College and the University of Central Florida. To accomplish this objective two survey instruments were administered to randomly selected licensed dentists and dental hygienists in the state of Florida. Dental hygienists represented the potential student base for the proposed programs, and dentists represented the potential and prospective employers of graduated students of the proposed programs. To determine demand and demand characteristics, one survey instrument was mailed to 1,000 dental hygienists who were randomly selected using SAS software from a population of N=12,066 dental hygienists actively licensed to practice in the state of Florida. This sample of hygienists was approximately 8.3% of the total population. Of the 1,000 samples, 134 (or 13.4%) were returned. Of the 134 surveys returned, 123 (n=123) were included in this study. Eleven surveys were not included because of a majority of missing data or because the respondent indicated he or she already possessed a Bachelor or Master degree. A Likert-scale questionnaire was sent to each group of actively licensed dentists and actively licensed dental hygienists from the state of Florida. Responses from dental hygienists were overwhelmingly positive towards the addition of the Bachelor of Science degree program with an online distance-learning component. Those in favor of the Bachelor of Science degree program also provided a favorable response towards adding a Master of Science degree program in dental hygiene. The dentists, as potential future employers, also showed strong support in their responses for the additional degree programs with an additional management track component and believed it would elevate the professional standards of the dental hygiene field.
Show less - Date Issued
- 2009
- Identifier
- CFE0002842, ucf:48048
- Format
- Document (PDF)
- PURL
- http://purl.flvc.org/ucf/fd/CFE0002842