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(1 - 5 of 5)
- Title
- ASSOCIATION BETWEEN UNIRHINAL OLFACTORY PROCESSING AND SELF-REPORTED EMPATHY IN SCHIZOPHRENIA.
- Creator
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Kamath, Vidyulata, Bedwell, Jeffrey, University of Central Florida
- Abstract / Description
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Empathy represents one multifaceted component of social cognition that is thought to be significantly impaired in individuals with schizophrenia. Psychophysical tasks of smell identification and hedonic processing of pleasant, neutral, and unpleasant odors share common neural networks involved in empathy. Therefore, we investigated the relationship between odor identification, odor ratings, and self-reported empathy in 25 outpatients with schizophrenia and 25 nonpsychiatric individuals. Group...
Show moreEmpathy represents one multifaceted component of social cognition that is thought to be significantly impaired in individuals with schizophrenia. Psychophysical tasks of smell identification and hedonic processing of pleasant, neutral, and unpleasant odors share common neural networks involved in empathy. Therefore, we investigated the relationship between odor identification, odor ratings, and self-reported empathy in 25 outpatients with schizophrenia and 25 nonpsychiatric individuals. Group differences on empathy scores and unirhinal smell identification performance (with hedonic and intensity ratings) were examined, along with the relationships between smell identification scores, self-reported empathy, and schizophrenia symptomatology. The preliminary findings suggest that individuals with schizophrenia display significant differences from controls on measures of self-reported empathy, odor identification, and hedonic ratings of odors. Deficits in self-reported global and affective empathy were influenced by group and sex, whereas cognitive empathy was reduced across all patients in comparison to controls. Patients displayed reduced unirhinal odor identification accuracy for pleasant but not neutral or unpleasant odors in comparison to controls. Central to the overall aim of the current study, a robust positive correlation was observed between left- and right-nostril hedonic ratings for pleasant odors and self-reported global and affective empathy scores across all participants. In patients, we also found a statistical trend between affective empathy and left-nostril identification accuracy across all odors. Collectively, the results lend support to the role of olfactory-limbic brain regions in the hedonic processing of odors and suggest that aberrant performance observed in schizophrenia may be related to abnormalities in the anatomical and physiological substrates that also subserve empathy.
Show less - Date Issued
- 2009
- Identifier
- CFE0002759, ucf:48132
- Format
- Document (PDF)
- PURL
- http://purl.flvc.org/ucf/fd/CFE0002759
- Title
- THE RELATIVE SENSITIVITY OF AN OLFACTORY IDENTIFICATION DEFICIT IN INDIVIDUALS WITH SCHIZOTYPAL PERSONALITY FEATURES.
- Creator
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Kamath, Vidyulata, Bedwell, Jeffrey, University of Central Florida
- Abstract / Description
-
Olfactory identification deficits have received recent attention as a potentially useful endophenotype for schizophrenia. Examination of this deficit in individuals with schizotypal personality features (SPF) offers an alternative approach to multiple confounds present when examining individuals with schizophrenia. The aim of the current study was to compare the relative sensitivity of performance on measures of olfaction identification and sustained attention to the presence of SPF. Twenty...
Show moreOlfactory identification deficits have received recent attention as a potentially useful endophenotype for schizophrenia. Examination of this deficit in individuals with schizotypal personality features (SPF) offers an alternative approach to multiple confounds present when examining individuals with schizophrenia. The aim of the current study was to compare the relative sensitivity of performance on measures of olfaction identification and sustained attention to the presence of SPF. Twenty-six undergraduates were defined as having SPF based on scoring in the top 10% of the Abbreviated Schizotypal Personality Questionnaire (SPQ-B; mean age 19.6, SD = 1.1; 62% female). These individuals were compared to twenty-six controls (scoring lower than half a standard deviation above the mean; mean age 19.8, SD = 1.6; 62% female). All participants were administered the Schizotypal Personality Disorder (SPD) section of the Structured Clinical Interview for DSM IV Axis II Personality Disorders (SCID-II). In addition, participants were administered the Brief Smell Identification Test (B-SIT) and a six-minute degraded-stimuli Continuous Performance Test (CPT). Group differences in performance indices of the CPT did not approach statistical significance. Similarly, there were no statistically significant group differences for males or females in performance on the B-SIT. Correlational analyses examined cognitive performance with a dimension score derived by summing quantitative ratings from the SPD items on the SCID-II. The SPD dimension score showed a statistically significant positive correlation with several performance indices of the CPT, including omission errors (rs(52) = .51, p < .001) and commission errors (rs(52) = .38, p < .005). In contrast, the B-SIT scores were not correlated with the SPD dimension score for males or females. Contrary to our hypothesis, results from the current study suggest that olfactory identification deficits may not represent a robust endophenotype consistently found in samples with schizotypal personality features. With regard to sustained attention, our differential findings suggest that schizotypal traits may be more adequately assessed through an interview by trained clinicians who use clinical judgment to determine the presence of phenotypic aspects of SPD (e.g., SCID-II), rather than relying on self-report measures (e.g., SPQ-B). Implications as well as limitations and future directions of these findings are discussed.
Show less - Date Issued
- 2007
- Identifier
- CFE0001675, ucf:47211
- Format
- Document (PDF)
- PURL
- http://purl.flvc.org/ucf/fd/CFE0001675
- Title
- Neurological Reactivity to Personalized Odors and Sounds in Combat-related Posttraumatic Stress Disorder.
- Creator
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Gramlich, Michael, Neer, Sandra, Beidel, Deborah, Bohil, Corey, Batien, Bryan, University of Central Florida
- Abstract / Description
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Functional near-infrared spectroscopy (fNIRS) is a neurophysiological procedure that offers immense clinical utility due to its cost effectiveness, ease of use, and mobile application. Using fNIRS to measure neurological reactions to personalized trauma-related cues might strengthen diagnostic screening, tailor treatment planning, and improve detection of remission among individuals with posttraumatic stress disorder (PTSD). Odors elicit strong emotional responses but remain underutilized in...
Show moreFunctional near-infrared spectroscopy (fNIRS) is a neurophysiological procedure that offers immense clinical utility due to its cost effectiveness, ease of use, and mobile application. Using fNIRS to measure neurological reactions to personalized trauma-related cues might strengthen diagnostic screening, tailor treatment planning, and improve detection of remission among individuals with posttraumatic stress disorder (PTSD). Odors elicit strong emotional responses but remain underutilized in clinical research. This fNIRS study examined whether personalizing combat-related odors and sounds to have a higher or lower match to distressing combat experiences increased the observed neurological effect among combat veterans with and without combat-related PTSD. This study gathered data from 58 male, right-handed combat veterans of Iraq or Afghanistan, ages 26 to 68, recruited from the community. The results indicated a significant increase in activation at the left ventral lateral prefrontal cortex (VLPFC) following an interaction between higher PTSD severity and higher match ratings for the combat-related odors (R2 = .20, p = .003; f2 = .25). Furthermore, the left VLPFC showed a significant increase in activation following an interaction between having a PTSD diagnosis and higher match ratings for the combat-related odors (R2 = .25, p = .005; f2 = .33). The findings for the combat-related sounds were less clear. The left VLPFC is associated with facilitating regulation of memory and emotional processes. Overall, the presentation of odors with higher similarity to distressing combat experiences altered the neurological response of the prefrontal cortex and may contribute to better understanding of the neurophysiological mechanisms of combat-related PTSD.
Show less - Date Issued
- 2019
- Identifier
- CFE0007809, ucf:52357
- Format
- Document (PDF)
- PURL
- http://purl.flvc.org/ucf/fd/CFE0007809
- Title
- Posttraumatic Stress Disorder or Combat Experience? A Functional Near-infrared Spectroscopy Study of Trauma-related Auditory and Olfactory Cues.
- Creator
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Gramlich, Michael, Neer, Sandra, Bowers, Clint, Beidel, Deborah, University of Central Florida
- Abstract / Description
-
While the clinical communities are aware of the prevalence of posttraumatic stress disorder (PTSD) among OEF/OIF/OND veterans, further efforts are necessary to bolster comprehensive strategies for assessment and treatment. The purpose of this study was to investigate whether a combat-related PTSD symptom provocation paradigm would elicit unique neurological responses via functional near-infrared spectroscopy across three groups (-) combat veterans with PTSD, combat veterans without PTSD, and...
Show moreWhile the clinical communities are aware of the prevalence of posttraumatic stress disorder (PTSD) among OEF/OIF/OND veterans, further efforts are necessary to bolster comprehensive strategies for assessment and treatment. The purpose of this study was to investigate whether a combat-related PTSD symptom provocation paradigm would elicit unique neurological responses via functional near-infrared spectroscopy across three groups (-) combat veterans with PTSD, combat veterans without PTSD, and nonmilitary participants without PTSD. Results indicated that combat veterans with PTSD demonstrated significant activation during exposure to a trauma-related sound compared to nonmilitary personnel at channels 14 (d = 1.03) and 15 (d = 1.30) and combat veterans without PTSD at channel 14 (d = 0.87). Specifically, this increased neural activation was approximately located in the right superior/medial prefrontal cortex (BA 9/10), associated with evaluating cue-familiarity and emotional detachment. Results were less clear with respect to a combat-related odor. These results suggest a specific neurophysiological response to trauma-related cues and if replicated, may offer a biomarker for combat-related PTSD. Such a response could provide incremental validity over diagnostic assessments alone and assist in planning and monitoring of treatment outcome.
Show less - Date Issued
- 2017
- Identifier
- CFE0006596, ucf:51297
- Format
- Document (PDF)
- PURL
- http://purl.flvc.org/ucf/fd/CFE0006596
- Title
- Do Olfactory Stimuli Increase Presence During Exposure Tasks: A Comparative Study.
- Creator
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Munyan, Benson, Neer, Sandra, Beidel, Deborah, Jentsch, Florian, University of Central Florida
- Abstract / Description
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Exposure therapy (ET) is an extensively studied and supported treatment for anxiety and trauma-related disorders. ET works by exposing the patient to the feared object or situation without any danger in order to overcome the related anxiety. Over the past few years, various technologies including head-mounted displays (HMDs), scent machines, and headphones have been used to augment the exposure therapy process by presenting multi-sensory cues (e.g., sights, smells, sounds) to increase the...
Show moreExposure therapy (ET) is an extensively studied and supported treatment for anxiety and trauma-related disorders. ET works by exposing the patient to the feared object or situation without any danger in order to overcome the related anxiety. Over the past few years, various technologies including head-mounted displays (HMDs), scent machines, and headphones have been used to augment the exposure therapy process by presenting multi-sensory cues (e.g., sights, smells, sounds) to increase the patient's sense of presence. While studies have shown that scents can elicit emotionally charged memories, no prior research could be identified that examined the effect of olfactory stimuli upon the patient's sense of presence during exposure tasks. In this study, the effect of olfactory stimuli on subject's sense of presence was assessed via psychophysiological response (electrodermal activity), visual scanning, and self-report measures. Linear Mixed Modeling showed relationships between olfactory stimuli and presence ratings as well as self-reported anxiety levels, but not visual scanning or physiological arousal. Recommendations were made for continued research in the union of olfactory stimuli, presence, and exposure therapy.
Show less - Date Issued
- 2015
- Identifier
- CFE0005850, ucf:50931
- Format
- Document (PDF)
- PURL
- http://purl.flvc.org/ucf/fd/CFE0005850
