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(1 - 7 of 7)
- Title
- A correlation study on the chronic obstructive pulmonary diseases.
- Creator
-
Capraun, Lynn Walter, Washington, David W., Natural Sciences
- Abstract / Description
-
Florida Technological University College of Natural Sciences Thesis; Data were extracted from medical records of 202 former patients of a well established central Florida general hospital. Records were selected so as to include an equal number of disease catagories dispersed equally over the two years. One hundred records were dated 1973 and 102 were dated 1976. Emphysema, chronic bronchitis, and asthma had been diagnosed in 67, 67, and 68 of the cases respectively. The age, sex, race,...
Show moreFlorida Technological University College of Natural Sciences Thesis; Data were extracted from medical records of 202 former patients of a well established central Florida general hospital. Records were selected so as to include an equal number of disease catagories dispersed equally over the two years. One hundred records were dated 1973 and 102 were dated 1976. Emphysema, chronic bronchitis, and asthma had been diagnosed in 67, 67, and 68 of the cases respectively. The age, sex, race, smoking habits, and occupations of the patients were recorded and crosstabulated with the diagnostic tests and subsequent treatment ordered by the various physicians. Most of the emphysematous patients were males over 50, the asthmatics were females under 30, and the bronchitics were older than 50 with an even sex distribution. Most of the emphysematous and bronchitic patients had smoked over 25 years, while only 13% of the asthmatics smoked. A majority of the chronic obstructive pulmonary disease patients complained of shortness of breath, were hospitalized ten days or less, treated four times a day with intermittent positive pressure breathing had little or no pulmonary rehabilitation, and survived. Respiratory care appeared to improve over the three-year period as judged by an increase in the frequency of blood gas monitoring and a reduction in the required ventilator times with improved techniques.
Show less - Date Issued
- 1978
- Identifier
- CFR0003461, ucf:53025
- Format
- Document (PDF)
- PURL
- http://purl.flvc.org/ucf/fd/CFR0003461
- Title
- Seal of North Carolina: Smoking Tobacco Marburg Bros.
- Date Created
- 1840-1880
- Identifier
- DP0015388
- Format
- Set of related objects
- PURL
- http://purl.flvc.org/ucf/fd/DP0015388
- Title
- Expression and functional evaluation of exendin 4 fused to cholera toxin B subunit in tobacco chloroplasts to treat type 2 diabetes.
- Creator
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Nityanandam, Ramya, Daniell, Henry, Naser, Saleh, Siddiqi, Shadab, University of Central Florida
- Abstract / Description
-
The prevalence of type 2 diabetes has been steadily increasing around the globe. Glucagon like peptide (GLP-1), a powerful incretin increases insulin secretion in a glucose dependent manner. But GLP-1 is subjected to rapid enzymatic degradation (half-life: 2 min in circulation). The commercially available GLP-1 analog, exenatide has a longer half life with potent insulinotropic effects (about 2.4 hr) which requires cold storage and daily subcutaneous injections. In this study, exendin 4 (EX4)...
Show moreThe prevalence of type 2 diabetes has been steadily increasing around the globe. Glucagon like peptide (GLP-1), a powerful incretin increases insulin secretion in a glucose dependent manner. But GLP-1 is subjected to rapid enzymatic degradation (half-life: 2 min in circulation). The commercially available GLP-1 analog, exenatide has a longer half life with potent insulinotropic effects (about 2.4 hr) which requires cold storage and daily subcutaneous injections. In this study, exendin 4 (EX4), lizard derived GLP-1R agonist, was expressed as cholera toxin B subunit (CTB)-fusion protein in chloroplasts of tobacco to facilitate transmucosal delivery in the gut by utilizing the ability of CTB pentamer to bind the GM1 receptors on the intestinal epithelium and to bioencapsulate EX4 within plant cells to confer protection in the digestive system. The LAMD tobacco leaves were bombarded with chloroplast vectors expressing modified EX4. The transgene integration was confirmed by PCR analysis and Southern blot analysis. Densitometric analysis revealed expression level of the protein varied from 9-13% of the total leaf protein depending on the developmental stage and time of harvest. The pentameric structure and functionality of CTB-EX4 fusion protein was confirmed by CTB-GM1 binding assay. The effect of transplastomic protein on insulin secretion was tested in ?-TC6, a mouse pancreatic cell line. The plant derived CTB-EX4, partially purified with anti-CTB antibody conjugated protein A beads, showed the increase of insulin ~ 2.5 fold increase when compared to untreated cells. The transplastomic protein showed a linear increase in insulin secretion comparable to the commercially available EX4. The current cost of treatment with EX4 varies between $1800-$2200, annually. Production of functional EX4 in plants should facilitate low cost orally deliverable form of this drug for treatment of type 2 diabetes.
Show less - Date Issued
- 2011
- Identifier
- CFE0004485, ucf:49306
- Format
- Document (PDF)
- PURL
- http://purl.flvc.org/ucf/fd/CFE0004485
- Title
- Tobacco Prevention and Cessation Policies and Youth Tobacco Use in Florida Public Schools.
- Creator
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Terry, Amanda, Zhang, Ning, Martin, Lawrence, Gammonley, Denise, Delnevo, Cristine, University of Central Florida
- Abstract / Description
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Tobacco use is the leading cause of preventable disease and premature death in the United States. In 2014, an estimated 16.8% of adults were current cigarette smokers, and 9.2% of high school students smoked cigarettes. Nearly 90% of smokers developed their habit as teenagers, and students' tobacco use in high school influences their behaviors later in adulthood. Smoking behaviors appear to be inseparable from the social environment, physical environment, small social groups, and cognitive...
Show moreTobacco use is the leading cause of preventable disease and premature death in the United States. In 2014, an estimated 16.8% of adults were current cigarette smokers, and 9.2% of high school students smoked cigarettes. Nearly 90% of smokers developed their habit as teenagers, and students' tobacco use in high school influences their behaviors later in adulthood. Smoking behaviors appear to be inseparable from the social environment, physical environment, small social groups, and cognitive and affective processes. Preventive strategies, such as advertising bans, clean indoor air laws, education programs, increased taxes, labeling limitations, mass-media campaigns, and youth access regulations, have been commonly used to prevent and reduce youth tobacco use nationwide. In Florida, local public school districts were authorized to develop new tobacco-free school policies through an amendment to the Florida Clean Indoor Air Act in June 2011. The purpose of this study was to determine the impact of the recently implemented smoking cessation policies, as well as individual-level factors and interpersonal-level factors, on youth tobacco use in Florida public schools. This study employed a pooled cross-sectional design with data for high school students from the Florida Youth Tobacco Survey (FYTS) in 2010 (n=37,797) and 2014 (n=32,930). It was guided by a theoretical framework based on the reasoned action approach and the social ecological model. Hierarchical logistic regression was used to analyze the data. The four models were binary logistic regression for cigarette use, multinomial logistic regression for cigarette use, binary logistic regression for cigar use, and multinomial logistic regression for cigar use. The results of this study support the importance of the individual-level constructs of background factors, behavioral beliefs, and control beliefs, the interpersonal-level construct of normative beliefs, and the policy-level construct of actual behavioral control when applied to youth tobacco use. These findings led to a better understanding of which policies, environments, and cognitions contribute to preventing and reducing teenage tobacco use, which is imperative in controlling the risks related to smoking and improving youth health. Now that the individual-level factors, interpersonal-level factors, and policy-level factors that contribute to youth tobacco use were recognized, preventative and therapeutic programs and interventions can be suggested and improved. This study provided evidence-based knowledge for improving public policies and interventional strategies towards smoking prevention and cessation for youth.
Show less - Date Issued
- 2016
- Identifier
- CFE0006188, ucf:51128
- Format
- Document (PDF)
- PURL
- http://purl.flvc.org/ucf/fd/CFE0006188
- Title
- Seal of North Carolina: Smoking Tobacco Marburg Bros.
- Date Created
- 1840-1880
- Identifier
- DP0015390
- Format
- Set of related objects
- PURL
- http://purl.flvc.org/ucf/fd/DP0015390
- Title
- Durham tobacco.
- Date Created
- 1840-1880
- Identifier
- DP0015391
- Format
- Image (JPEG)
- PURL
- http://purl.flvc.org/ucf/fd/DP0015391
- Title
- PERCEPTIONS AND THEIR ROLE IN CONSUMER DECISION-MAKING.
- Creator
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Khaddaria, Raman, Gerking, Shelby, University of Central Florida
- Abstract / Description
-
This dissertation is an empirical investigation into the roles that different quantifiable and measurable perceptions play in defining individual behavior across a variety of decision-making contexts. In particular, the focus lies on smokers and the choices they make with regard to smoking and beyond. Chapter 1 analyzes a nationally representative sample of adults (23 years and older) in the United States, pertaining to the Annenberg Perception of Tobacco Risk Survey II (1999-2000). It is...
Show moreThis dissertation is an empirical investigation into the roles that different quantifiable and measurable perceptions play in defining individual behavior across a variety of decision-making contexts. In particular, the focus lies on smokers and the choices they make with regard to smoking and beyond. Chapter 1 analyzes a nationally representative sample of adults (23 years and older) in the United States, pertaining to the Annenberg Perception of Tobacco Risk Survey II (1999-2000). It is observed that three dimensions to smoking behavior viz., risk, temporality and addiction, interact to determine the smoking status of an individual. Although previous studies mostly looked into each of these dimensions in isolation, in this chapter, we empirically illustrate how perceptions on risk, time dimensions and addiction, jointly influence the smoking behavior of adults. Chapter 2 casts the smoker in the role of a parent and explores parental behavior towards the general health-risks facing their children. Using the dataset from a survey (2009), conducted in Orlando, Florida, on parents, having at least one child aged between 1 and 16 years, the chapter arrives at two findings relevant for policy: i) In each of the 'smoker' and 'non-smoker' parent categories, parents exhibit equal concern for themselves and their children, and ii) the level of concern shown by smoker-parents, towards health-risks faced by their children, is the same as that shown by their non-smoking counterparts. The analysis in this chapter also affirms the need to incorporate subjective risk assessment in willingness-to-pay (WTP) exercises to facilitate a deeper behavioral analysis of health risk valuation. Lastly, in Chapter 3, we focus on the issue of quantitative assessment of the perception of health risks from smoking. Particular interest lies in understanding how variants of a metric - namely, a survey question - have been employed in academic studies and industry-surveys, in order to measure smoking-related risk-perceptions. In the process of reviewing select tobacco-industry survey records, we analyze the implications of different features of this metric, (e.g., use of a 'probe', the 'Don't Know' option), and various interview modes (e.g. telephonic, face-to-face), for the estimates of perceived risk arrived at in these studies. The review makes clear that two aspects of health risks from smoking - the risk of contracting a smoking-related disease, as against the risk of prematurely dying from it conditional upon getting affected - have not been jointly explored so far. The dataset obtained from the Family Heart Disease and Prevention Survey (November 2010-March 2011), provides a unique opportunity to explore these two kinds of probabilities, particularly with regard to the risks of lung-cancer from smoking. Chapter 3 concludes by illustrating how individuals evaluate both these aspects of health-risks. While the probability of getting lung-cancer is found to be overestimated in conjunction with previous studies, the conditional probability of premature death is severely underestimated. Additionally, it is found that individuals' subjective assessments of either of these risk aspects predict smoking behavior in an identical manner. This calls into question the so-called 'rationality' of smoking decisions with implications for policies designed for the control of tobacco consumption.
Show less - Date Issued
- 2011
- Identifier
- CFE0003918, ucf:48736
- Format
- Document (PDF)
- PURL
- http://purl.flvc.org/ucf/fd/CFE0003918
