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Alcohol Consumption, Frailty, and the Mediating Role of C-Reactive Protein in Older Adults
Title
Alcohol Consumption, Frailty, and the Mediating Role of C-Reactive Protein in Older Adults.
Creator
Shah, Mona, Paulson, Daniel, Cassisi, Jeffrey, Sims, Valerie, University of Central Florida
Abstract / Description
Frailty is a well-established indicator of late-life decline and is accompanied by higher rates of comorbidity and disability. Meanwhile, an estimated 41% of adults over the age of 65 report consuming alcohol (-) an identified health risk and protective factor depending on dosage. Given that the demographic group of older Americans is projected to double by the year 2050, identification of frailty risk and protective factors is imperative. The goals of this thesis are to: (1) identify how...
Show moreFrailty is a well-established indicator of late-life decline and is accompanied by higher rates of comorbidity and disability. Meanwhile, an estimated 41% of adults over the age of 65 report consuming alcohol (-) an identified health risk and protective factor depending on dosage. Given that the demographic group of older Americans is projected to double by the year 2050, identification of frailty risk and protective factors is imperative. The goals of this thesis are to: (1) identify how varying levels of alcohol consumption relate to frailty, and (2) elucidate a possible mechanism that accounts for the relationship between alcohol consumption and frailty. A sample of stroke-free participants over the age of 65 was identified from the Health and Retirement Study. Study 1 utilized stepwise logistic regression models to identify predictors of prevalent frailty at baseline (2000), and of incident frailty 4, 8, and 12 years later. For both males and females, significant predictors of frailty at all years included age, depressive symptomatology, and medical burden score. In addition, BMI was a significant predictor of frailty for females at all years. With respect to alcohol use, results revealed that drinking 1-7 drinks per week had a protective effect for females at baseline (OR=0.50) and 12 years later (OR=0.75); however, no such protective effects were found for males. Given that extant research has identified CRP as a mediator between the relationship of moderate alcohol use and cardiovascular health benefits, Study 2 used a cross-sectional sample from the 2008 wave to examine the potential mediating role of CRP between moderate alcohol use and reduced frailty risk. Results from structural equation modeling support the hypothesized model that moderate alcohol is associated with less frailty, and that this relationship is partially mediated by CRP levels. Overall findings suggest that moderate alcohol use confers health benefits for females by reducing frailty risk and that CRP is one mechanism by which alcohol use may confer protective effects for frailty. These results provide a starting place in an effort to better understand the protective effects of moderate alcohol use and can assist in improving prevention and treatment efforts for older adults by preventing or prolonging the onset of age-related diseases. Future research should further examine the relationship between alcohol use and frailty and determine if CRP mediates the relationship between moderate alcohol use and other beneficial health outcomes.
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Date Issued
2015
Identifier
CFE0006000, ucf:51027
Format
Document (PDF)
PURL
http://purl.flvc.org/ucf/fd/CFE0006000
PUBS, PUNTERS, AND PINTS: ANTHROPOLOGICAL REFLECTIONS ON PUB LIFE IN IRELAND
Title
PUBS, PUNTERS, AND PINTS: ANTHROPOLOGICAL REFLECTIONS ON PUB LIFE IN IRELAND.
Creator
Cucchiara, Jason, Matejowsky, Ty, University of Central Florida
Abstract / Description
Ireland is a country with a rich and unique cultural heritage. It is difficult to imagine that certain facets of Irish culture (e.g. Saint Patrick's Day, the Blarney Stone, or the Ring of Kerry) can ever be taken for granted since they are so widely recognized internationally. One common feature of Irish life that possibly warrants more scholarly attention is the public house or pub. Much has been written about pubs as quaint institutions in popular literature and fiction. Curiously, they...
Show moreIreland is a country with a rich and unique cultural heritage. It is difficult to imagine that certain facets of Irish culture (e.g. Saint Patrick's Day, the Blarney Stone, or the Ring of Kerry) can ever be taken for granted since they are so widely recognized internationally. One common feature of Irish life that possibly warrants more scholarly attention is the public house or pub. Much has been written about pubs as quaint institutions in popular literature and fiction. Curiously, they remain largely overlooked as vital aspects of Irish culture by anthropologists and others in the social sciences. In many ways, socio-cultural research on pub life in Ireland is woefully under examined. In an effort to better evaluate the significance of traditional pub life to Irish culture, my thesis seeks to integrate and critically assess the existing socio-cultural literature on Irish pub life. Such work will not only help highlight both the commonalities and discrepancies within this area of study, it will more significantly identify those areas of Irish pub life that can benefit from further academic investigation. Two recent trips to Ireland in September 2004 and May 2006, allowed me to observe important aspects of pub life first hand. It became apparent from these encounters that, like the history of Ireland itself, local pubs have a rich historical foundation. Many of the pubs that I visited have been in existence or operational since the Middle Ages. Based on this longevity, one can reasonably argue that pubs in Ireland function largely as locales of social significance and cultural reproduction, not just centers of recreational drinking. Using my travel experience as a starting point for the critical analysis phase of this thesis project, I have developed three general research questions that I will explore to varying degrees in the context of this work. These are: (1) what are the origins of pubs in Ireland?; (2) what explicit and implicit functions do pubs serve in Irish communities?; and (3) what possible developments are likely to affect Irish pubs in the near and distant future?
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Date Issued
2009
Identifier
CFE0002578, ucf:48255
Format
Document (PDF)
PURL
http://purl.flvc.org/ucf/fd/CFE0002578