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(1 - 5 of 5)
- Title
- ETHANOL LOCK THERAPY IN THE TREATMENT AND PREVENTION OF CATHETER-RELATED BLOODSTREAM INFECTIONS.
- Creator
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Anderson, Breanna, Heglund, Stephen, University of Central Florida
- Abstract / Description
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Ethanol lock therapy is a novel technique that is being studied for its efficacy in eradicating catheter related bloodstream infections. A systematic review of interdisciplinary studies from CINAHL, Medline, Academic Search Premier, Biological Abstracts, and Web of Knowledge databases was performed. This meta-analysis examined the findings of thirty-five studies on ethanol lock therapy. Twenty-six of these studies compared ethanol to a placebo and nine studies performed a direct comparison of...
Show moreEthanol lock therapy is a novel technique that is being studied for its efficacy in eradicating catheter related bloodstream infections. A systematic review of interdisciplinary studies from CINAHL, Medline, Academic Search Premier, Biological Abstracts, and Web of Knowledge databases was performed. This meta-analysis examined the findings of thirty-five studies on ethanol lock therapy. Twenty-six of these studies compared ethanol to a placebo and nine studies performed a direct comparison of ethanol to other agents frequently used in antimicrobial lock technique. Ethanol lock therapy was shown to be effective as both a prophylactic therapy and as an active treatment in eradicating biofilms of organisms that frequently cause catheter-related blood stream infections, including Staphylococcus epidermis, Staphylococcus aureus, Klebsiella pneumonia, Pseudomonas aeruginosa, E. coli, and Candida albicans. Ethanol has been shown to have a synergistic effect with several other antimicrobial agents. The majority of studies examined in this thesis have found that ethanol has equal or greater efficacy to several antibiotic and antimicrobial agents used in practice and should therefore be considered for the treatment of catheter-related blood stream infections.
Show less - Date Issued
- 2012
- Identifier
- CFH0004183, ucf:44845
- Format
- Document (PDF)
- PURL
- http://purl.flvc.org/ucf/fd/CFH0004183
- Title
- COMPARATIVE STUDY OF ETHANOL AND METHANOL ELECTRO-OXIDATION ON A PLATINUM/CERIA COMPOSITE ELECTRODE IN ALKALINE AND ACID SOLUTIONS: ELECTRO-CATALYTIC PERFORMANCE AND REACTION KINETICS.
- Creator
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Hidalgo, Carlos, Diaz, Diego, University of Central Florida
- Abstract / Description
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A comparative study of the electro-oxidation of ethanol and methanol was carried out on a Pt/ceria composite electrode prepared by electro-deposition. Modification of the Pt electrode was realized by co-deposition from a 1.0 mM K2PtCl6 solution that also contained a 20 mM suspension of ceria. The electro-catalytic activities and stabilities of the Pt/ceria catalyst towards ethanol electro-oxidation reactions (EOR) and methanol electro-oxidation reactions (MOR) were investigated by...
Show moreA comparative study of the electro-oxidation of ethanol and methanol was carried out on a Pt/ceria composite electrode prepared by electro-deposition. Modification of the Pt electrode was realized by co-deposition from a 1.0 mM K2PtCl6 solution that also contained a 20 mM suspension of ceria. The electro-catalytic activities and stabilities of the Pt/ceria catalyst towards ethanol electro-oxidation reactions (EOR) and methanol electro-oxidation reactions (MOR) were investigated by potentiodynamic and potentiostatic methods in 0.5 M sulfuric acid and 1.0 M sodium hydroxide solutions at various concentrations of ethanol and methanol. The kinetics of ethanol and methanol on a Pt/ceria composite electrode were measured in 0.5 M sulfuric acid and 1.0 M sodium hydroxide solutions using a rotating disk electrode (RDE). Cyclic voltammetry was employed in temperatures ranging from 15 to 55°C to provide quantitative and qualitative information on the kinetics of alcohol oxidation. The temperature dependence of the electro-catalytic activities afforded the determination of apparent activation energies for ethanol and methanol oxidation.
Show less - Date Issued
- 2011
- Identifier
- CFE0003628, ucf:48853
- Format
- Document (PDF)
- PURL
- http://purl.flvc.org/ucf/fd/CFE0003628
- Title
- A Production and Cost Modeling Methodology of 2nd Generation Biofuel in the United States.
- Creator
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Poole, David, Kincaid, John, Mollaghasemi, Mansooreh, Geiger, Christopher, University of Central Florida
- Abstract / Description
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The use of biofuels in the United States has increased dramatically in the last few years. The largest source of feedstock for ethanol to date has been corn. However, corn is also a vitally important food crop and is used commonly as feed for cattle and other livestock. To prevent further diversion of an important food crop to production of ethanol, there is great interest in developing commercial-scale technologies to make ethanol from non-food crops, or other suitable plant material. This...
Show moreThe use of biofuels in the United States has increased dramatically in the last few years. The largest source of feedstock for ethanol to date has been corn. However, corn is also a vitally important food crop and is used commonly as feed for cattle and other livestock. To prevent further diversion of an important food crop to production of ethanol, there is great interest in developing commercial-scale technologies to make ethanol from non-food crops, or other suitable plant material. This is commonly referred to as biomass. A review is made of lignocellulosic sources being considered as feedstocks to produce ethanol. Current technologies for pretreatment and hydrolysis of the biomass material are examined and discussed. Production data and cost estimates are culled from the literature, and used to assist in development of mathematical models for evaluation of production ramp-up profiles, and cost estimation. These mathematical models are useful as a planning tool, and provide a methodology to estimate monthly production output and costs for labor, capital, operations and maintenance, feedstock, raw materials, and total cost. Existing credits for ethanol production are also considered and modeled. The production output in liters is modeled as a negative exponential growth curve, with a rate coefficient providing the ability to evaluate slower, or faster, growth in production output and its corresponding effect on monthly cost. The capital and labor costs per unit of product are determined by dividing the monthly debt service and labor costs by that month?s production value. The remaining cost components change at a constant rate in the simulation case studies. This methodology is used to calculate production levels and costs as a function of time for a 25 million gallon per year capacity cellulosic ethanol plant. The parameters of interest are calculated in MATLAB with a deterministic, continuous system simulation model. Simulation results for high, medium, and low cost case studies are included. Assumptions for the model and for each case study are included and some comparisons are made to cost estimates in the literature. While the cost per unit of product decreases and production output increases over time, some reasonable cost values are obtained by the end of the second year for both the low and medium cost case studies. By the end of Year 2, total costs for those case studies are $0.48 per liter and $0.88 per liter, respectively. These cost estimates are well within the reported range of values from the reviewed literature sources. Differing assumptions for calculations made by different sources make a direct cost comparison with the outputs of this modeling methodology extremely difficult. Proposals for reducing costs are introduced. Limitations and shortcomings of the research activity are discussed, along with recommendations for potential future work in improving the simulation model and model verification activities. In summary, the author was not able to find evidence?within the public domain?of any similar modeling and simulation methodology that uses a deterministic, continuous simulation model to evaluate production and costs as a function of time. This methodology is also unique in highlighting the important effect of production ramp-up on monthly costs for capital (debt service) and labor. The resultant simulation model can be used for planning purposes and provides an independent, unbiased estimate of cost as a function of time.
Show less - Date Issued
- 2012
- Identifier
- CFE0004424, ucf:49321
- Format
- Document (PDF)
- PURL
- http://purl.flvc.org/ucf/fd/CFE0004424
- Title
- Electrochemical Studies of Nanoscale Composite Materials as Electrodes in PEM Fuel Cells.
- Creator
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Anderson, Jordan, Zhai, Lei, Blair, Richard, Hampton, Michael, Zou, Shengli, Seal, Sudipta, University of Central Florida
- Abstract / Description
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Polymer electrolyte membrane fuel cells (PEMFCs) have recently acquired much attention as alternatives to combustion engines for power conversion. The primary interest in fuel cell technology is the possibility of 60% power conversion efficiency as compared to the 30% maximum theoretical efficiency limited to combustion engines and turbines. Although originally conceived to work with hydrogen as a fuel, difficulties relating to hydrogen storage have prompted much effort in using other fuels....
Show morePolymer electrolyte membrane fuel cells (PEMFCs) have recently acquired much attention as alternatives to combustion engines for power conversion. The primary interest in fuel cell technology is the possibility of 60% power conversion efficiency as compared to the 30% maximum theoretical efficiency limited to combustion engines and turbines. Although originally conceived to work with hydrogen as a fuel, difficulties relating to hydrogen storage have prompted much effort in using other fuels. Small organic molecules such as alcohols and formic acid have shown promise as alternatives to hydrogen in PEMFCs due to their higher stability at ambient conditions. The drawbacks for using these fuels in PEMFCs are related to their incomplete oxidation mechanisms, which lead to the production of carbon monoxide (CO). When carbon monoxide is released in fuel cells it binds strongly to the platinum anode thus limiting the adsorption and subsequent oxidation of more fuel. In order to promote the complete oxidation of fuels and limit poisoning due to CO, various metal and metal oxide catalysts have been used.Motivated by promising results seen in fuel cell catalysis, this research project is focused on the design and fabrication of novel platinum-composite catalysts for the electrooxidation of methanol, ethanol and formic acid. Various Pt-composites were fabricated including Pt-Au, Pt-Ru, Pt-Pd and Pt-CeO2 catalysts. Electrochemical techniques were used to determine the catalytic ability of each novel composite toward the electrooxidation of methanol, ethanol and formic acid. This study indicates that the novel composites all have higher catalytic ability than bare Pt electrodes. The increase in catalytic ability is mostly attributed to the increase in CO poison tolerance and promotion of the complete oxidation mechanism of methanol, ethanol and formic acid. Formulations including bi- and tri-composite catalysts were fabricated and in many cases show the highest catalytic oxidation, suggesting tertiary catalytic effects. The combination of bi-metallic composites with ceria also showed highly increased catalytic oxidation ability. The following dissertation expounds on the relationship between composite material and the electrooxidation of methanol, ethanol and formic acid. The full electrochemical and material characterization of each composite electrode is provided.
Show less - Date Issued
- 2012
- Identifier
- CFE0004510, ucf:49264
- Format
- Document (PDF)
- PURL
- http://purl.flvc.org/ucf/fd/CFE0004510
- Title
- Remediation of Polychlorinated Biphenyl (PCB) Contaminated Building Materials Using Non-metal and Activated Metal Treatment Systems.
- Creator
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Legron-Rodriguez, Tamra, Yestrebsky, Cherie, Clausen, Christian, Elsheimer, Seth, Sigman, Michael, Chopra, Manoj, Quinn, Jacqueline, University of Central Florida
- Abstract / Description
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PCBs are recalcitrant compounds of no known natural origin that persist in the environment despite their ban by the United States Environmental Protection Agency in 1979 due to negative health effects. Transport of PCBs from elastic sealants into concrete, brick, and granite structures has resulted in the need for a technology capable of removing these PCBs from the materials. This research investigated the use of a nonmetal treatment system (NMTS) and an activated metal treatment system ...
Show morePCBs are recalcitrant compounds of no known natural origin that persist in the environment despite their ban by the United States Environmental Protection Agency in 1979 due to negative health effects. Transport of PCBs from elastic sealants into concrete, brick, and granite structures has resulted in the need for a technology capable of removing these PCBs from the materials. This research investigated the use of a nonmetal treatment system (NMTS) and an activated metal treatment system (AMTS) for the remediation and degradation of PCBs from concrete, brick, and granite affixed with PCB-laden caulking. The adsorption of PCBs onto the components of concrete and the feasibility of ethanol washing were also investigated.NMTS is a sorbent paste containing ethanol, acetic acid, and fillers that was developed at the University of Central Florida Environmental Chemistry Laboratory for the in situ remediation of PCBs. Combining NMTS with magnesium results in an activated treatment system used for reductive dechlorination of PCBs. NMTS was applied to laboratory-prepared concrete as well as field samples by direct contact as well as by a novel sock-type delivery. The remediation of PCBs from field samples using NMTS and AMTS resulted in a 33-98% reduction for concrete, a 65-70% reduction for brick, and an 89% reduction in PCB concentration for granite. The limit of NMTS for absorption of Aroclor 1254 was found to be roughly 22,000 mg Aroclor 1254 per kg of treatment system or greater. The activated treatment system resulted in a 94% or greater degradation of PCBs after seven days with the majority of degradation occurring in the first 24 hours. The adsorption of PCBs to individual concrete components (hydrated cement, sand, crushed limestone, and crushed granite) was found to follow the Freundlich isotherm model with greater adsorption to crushed limestone and crushed granite compared to hydrated cement and sand. Ethanol washing was shown to decrease the concentration of laboratory-prepared concrete by 68% and the concentration of PCBs in the ethanol wash were reduced by 77% via degradation with an activated magnesium system.
Show less - Date Issued
- 2013
- Identifier
- CFE0005197, ucf:50625
- Format
- Document (PDF)
- PURL
- http://purl.flvc.org/ucf/fd/CFE0005197
