Current Search: stroke (x)
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Title
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THE PSYCHOSOCIAL EFFECTS OF APHASIA ON THE CAREGIVER.
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Creator
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Ferrara, Lauren A, Whiteside, Janet D., Wharton, Tracy; Zraick, Richard, University of Central Florida
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Abstract / Description
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Studies have investigated the physical and emotional wellbeing of family members and spouses who care for persons with stroke (Bakas, et al. 2006). Literature shows burden of care is high in role reversal and depression is frequent. Variables that affect the caregiver burden with persons with aphasia (PWA) have not been identified prior to this study. Results from caregiver interviews found six themes, some which have not been identified prior, such as feelings of optimism.
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Date Issued
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2017
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Identifier
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CFH2000175, ucf:45968
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Format
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Document (PDF)
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PURL
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http://purl.flvc.org/ucf/fd/CFH2000175
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Title
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Barriers to timely administration of thrombolytics in acute ischemic stroke patients.
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Creator
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Joseph, Elizabeth, Talbert, Steven, Chase, Susan, Ullah, Saif, University of Central Florida
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Abstract / Description
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Stroke is a leading cause of long term disability in the United States. The therapeutic benefits of intravenous thrombolytics is time dependent in an acute ischemic stroke patient and is an important determinant of 90 day and one year functional outcomes. This study investigated areas in the stroke alert process of a community based primary stroke care center that resulted in the delay of administration of thrombolytics within 60 minutes of an acute ischemic stroke patient's arrival to the...
Show moreStroke is a leading cause of long term disability in the United States. The therapeutic benefits of intravenous thrombolytics is time dependent in an acute ischemic stroke patient and is an important determinant of 90 day and one year functional outcomes. This study investigated areas in the stroke alert process of a community based primary stroke care center that resulted in the delay of administration of thrombolytics within 60 minutes of an acute ischemic stroke patient's arrival to the emergency room. A retrospective descriptive design was utilized and chart reviews were done on 40 patients that received thrombolytics in the emergency room. Patient characteristics and time variables associated with the various steps in the stroke alert process were extracted. Findings showed that only 7.5% of the patients received thrombolytics within the recommended 60 minutes, with the longest time interval associated with time from arrival to the emergency room to time of evaluation by teleneurologist. There were no significant differences in the characteristics of patients who received thrombolytics within 60 minutes and those patients that received thrombolytics after 60 minutes. Recommendations were made for changes in organizational and practice strategies to improve timely administration, and for future research involving the effects of quality improvement initiatives.
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Date Issued
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2012
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Identifier
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CFE0004390, ucf:49406
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Format
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Document (PDF)
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PURL
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http://purl.flvc.org/ucf/fd/CFE0004390
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Title
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Caregiver-proxy and individual with aphasia self-report agreement on the modified perceived stress scale and mutuality scale.
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Creator
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Hernandez, Nelson, Wilson, Lauren Bislick, Engelhoven, Amy, Hunting Pompon, Rebecca, Troche, Joshua, University of Central Florida
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Abstract / Description
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The level of agreement proxy-caregivers have with individuals with aphasia (IWAs) on a measure of perceived stress has yet to be systematically investigated. According to the extant literature, there is less agreement on psychosocial domains between proxy-caregivers and IWAs. In addition, high levels of mutuality have been strongly associated with low levels of stress in stroke survivors; however, these studies are not been specific to IWAs. The proposed study sought to examine the degree of...
Show moreThe level of agreement proxy-caregivers have with individuals with aphasia (IWAs) on a measure of perceived stress has yet to be systematically investigated. According to the extant literature, there is less agreement on psychosocial domains between proxy-caregivers and IWAs. In addition, high levels of mutuality have been strongly associated with low levels of stress in stroke survivors; however, these studies are not been specific to IWAs. The proposed study sought to examine the degree of agreement between proxy-caregiver reports and IWAs' perceived stress using a modified stress scale specifically for IWAs. This study also examined the relationship between perceived stress and mutuality of the relationship between the caregiver and IWAs. The modified Perceived Stress Scale (mPSS), a proxy version of the mPSS, and the Mutuality Scale (MS) were administered to 12 dyads. An independent sample t-test was conducted to determine if there were significant differences in perceived stress and mutuality as reported by the caregiver, proxy-caregiver and IWA. A Pearson correlation was performed to determine the level of agreement across questionnaires. Results show a moderate correlation on mPSS ratings between the proxy-caregiver and IWA. On average, proxy ratings on the mPSS were significantly higher than reports from IWAs. There was strong agreement on mutuality among the dyads and a moderate correlation between mutuality agreement and proxy agreement. Finally, there was a moderate correlation between the caregiver's mPSS score and increased disagreement between the proxy-caregiver and the IWA's mPSS score. These findings suggest a moderate agreement on perceived stress among caregivers and IWAs. Differences in agreement on perceived stress for proxy-caregiver and IWAs were minimized when perceived mutuality between the dyads were high. Further, caregivers were more likely to overestimate the perceived stress of IWAs when their own mPSS ratings were high. Study limitations and future directions are also discussed.
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Date Issued
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2019
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Identifier
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CFE0007652, ucf:52464
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Format
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Document (PDF)
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PURL
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http://purl.flvc.org/ucf/fd/CFE0007652
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Title
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Expanding and Shedding the Self: Processing Selfdom Through Painting.
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Creator
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Lucey, Theresa, Poindexter, Carla, Lotz, Theo, Burrell, Jason, University of Central Florida
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Abstract / Description
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The absurd perpetual struggle, although entirely without hope of resolution, is the key to life's meaning, or perhaps, meaninglessness. The artist must work to live and live to work and find their place in an absurd world. Find joy in the questioning act of art making, make no attempt to escape the meaninglessness through pacifism, and face the chaos with awareness. I employ self-portraiture as a means to dig deeply into my experience and response to living. Self-portraiture morphs along with...
Show moreThe absurd perpetual struggle, although entirely without hope of resolution, is the key to life's meaning, or perhaps, meaninglessness. The artist must work to live and live to work and find their place in an absurd world. Find joy in the questioning act of art making, make no attempt to escape the meaninglessness through pacifism, and face the chaos with awareness. I employ self-portraiture as a means to dig deeply into my experience and response to living. Self-portraiture morphs along with my experiences and keeps a record of my thought patterns. My body of work is the harvest of my seeds of reflection. Tying together past influences, existential questioning, and a Sisyphean philosophy to a life of art making, I unravel the inner outcomes of my studio practice. It is in retrospect, through distance, that these connections are fully realized.
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Date Issued
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2019
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Identifier
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CFE0007490, ucf:52657
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Format
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Document (PDF)
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PURL
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http://purl.flvc.org/ucf/fd/CFE0007490
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Title
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EXPLORING ENVIRONMENTAL HEAT INJURIES IN THE PEDIATRIC POPULATION.
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Creator
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Bowman, Jennifer, Heglund, Stephen, University of Central Florida
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Abstract / Description
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Children are considered a vulnerable population in society. While thermoregulation in children is similar to that of an adult, children are vulnerable to heat-related illness. Student athletes have been found to be particularly vulnerable to heat-related illness for numerous reasons, including intense outdoor play. Football players are perhaps the most at-risk population of student athletes due to the intense physical requirements, outdoor practice during the hottest months of the year, and...
Show moreChildren are considered a vulnerable population in society. While thermoregulation in children is similar to that of an adult, children are vulnerable to heat-related illness. Student athletes have been found to be particularly vulnerable to heat-related illness for numerous reasons, including intense outdoor play. Football players are perhaps the most at-risk population of student athletes due to the intense physical requirements, outdoor practice during the hottest months of the year, and the extensive protective equipment required. By conducting a literature review on the subject of pediatric heat illness, the purpose of this thesis is to explore evidenced based research and guidelines regarding heat-related illness prevention. This review of literature was conducted through the utilization of the University of Central Florida's online databases using the EBSCOhost platform of: CINAHL Plus with Full Text, Cochrane Database of Systematic Reviews, ERIC, Health Source: Nursing/Academic Edition, MEDLINE, PsycINFO and SPORTDiscus. This thesis is unique because it does not focus on an individual sport; rather, it focuses on pediatric athletes from various disciplines. The prevalence, pathophysiology, prevention, and treatment of heat-related injuries are complex phenomena requiring the attention of law makers, athletic associations, school officials, coaches, athletic trainers, parents, and students.
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Date Issued
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2019
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Identifier
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CFH2000568, ucf:45667
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Format
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Document (PDF)
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PURL
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http://purl.flvc.org/ucf/fd/CFH2000568
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Title
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National Collegiate Athletic Association Strength and Conditioning Coaches' Knowledge and Practices Regarding Prevention and Recognition of Exertional Heat Stroke.
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Creator
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Valdes, Anna, Hoffman, Jay, Boote, David, Fisher, Thomas, Mitchell, Debby, University of Central Florida
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Abstract / Description
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The purpose of this study was to assess and determine the current level of knowledge that National Collegiate Athletic Association (NCAA) Strength and Conditioning Coaches (SCCs) possess regarding exertional heat stroke (EHS) prevention and recognition and to determine if SCC certification type had any effect. Major findings of this study support the view that SCCs need more preparation, education and training to increase their competency in preventing and recognizing EHS. Research found that...
Show moreThe purpose of this study was to assess and determine the current level of knowledge that National Collegiate Athletic Association (NCAA) Strength and Conditioning Coaches (SCCs) possess regarding exertional heat stroke (EHS) prevention and recognition and to determine if SCC certification type had any effect. Major findings of this study support the view that SCCs need more preparation, education and training to increase their competency in preventing and recognizing EHS. Research found that there was no significant difference in scores on the EHS scale based on SCC certification (CSCS vs. SCCC) after accounting for experience, education or division but the CSCS certified professionals scored higher on all the factors as compared to SCCs without the CSCS.. The major key finding was that SCCs lacked essential knowledge to prevent or recognize EHS. Furthermore, the study defines relevant EHS prevention and recognition competencies that an undergraduate curriculum, graduate curriculum and professional certification providers, should include and emphasize in their preparation programs.
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Date Issued
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2013
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Identifier
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CFE0004766, ucf:49790
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Format
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Document (PDF)
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PURL
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http://purl.flvc.org/ucf/fd/CFE0004766
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Title
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COMPUTATIONAL FLUID DYNAMICS INVESTIGATION OF THE ORIENTATION OF A PEDIATRIC LEFT VENTRICLE ASSIST DEVICE CANNULA TO REDUCE STROKE EVENTS.
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Creator
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Guimond, Stephen, Kassab, Alain, University of Central Florida
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Abstract / Description
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Ventricle Assist Devices (VADs), which are typically either axial or centrifugal flow pumps implanted on the aortic arch, have been used to support patients who are awaiting cardiac transplantation. Success of the apparatus in the short term has led to long term use. Despite anticoagulation measures, blood clots (thrombi) have been known to form in the device itself or inside of the heart. The Ventricle Assist Devices supply blood flow via a conduit (cannula) implanted on the ascending aorta....
Show moreVentricle Assist Devices (VADs), which are typically either axial or centrifugal flow pumps implanted on the aortic arch, have been used to support patients who are awaiting cardiac transplantation. Success of the apparatus in the short term has led to long term use. Despite anticoagulation measures, blood clots (thrombi) have been known to form in the device itself or inside of the heart. The Ventricle Assist Devices supply blood flow via a conduit (cannula) implanted on the ascending aorta. Currently, the implantation angle of the VAD cannula is not taken into consideration. Since the VADs supply a significant amount of blood flow to the aorta, the implantation angle can greatly affect the trajectory of the formed thrombi as well as the cardiac flow field inside of the aortic arch. This study aims to vary the implantation angle of a pediatric Left Ventricle Assist Device (LVAD) through a series of computational fluid dynamics (CFD) software simulations focusing on the aortic arch and its branching arteries of a 20 kg pediatric patient in order to reduce the occurrence of stroke.
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Date Issued
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2012
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Identifier
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CFH0004305, ucf:45044
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Format
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Document (PDF)
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PURL
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http://purl.flvc.org/ucf/fd/CFH0004305
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Title
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Hybrid Multi-Objective Optimization of Left Ventricular Assist Device Outflow Graft Anastomosis Orientation to Minimize Stroke Rate.
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Creator
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Lozinski, Blake, Kassab, Alain, Mansy, Hansen, DeCampli, William, University of Central Florida
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Abstract / Description
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A Left Ventricular Assist Device (LVAD) is a mechanical pump that is utilized as a bridge to transplantation for patients with a Heart Failure (HF) condition. More recently, LVADs have been also used as destination therapy and have provided an increase in the quality of life for patients with HF. However, despite improvements in VAD design and anticoagulation treatment, there remains a significant problem with VAD therapy, namely drive line infection and thromboembolic events leading to...
Show moreA Left Ventricular Assist Device (LVAD) is a mechanical pump that is utilized as a bridge to transplantation for patients with a Heart Failure (HF) condition. More recently, LVADs have been also used as destination therapy and have provided an increase in the quality of life for patients with HF. However, despite improvements in VAD design and anticoagulation treatment, there remains a significant problem with VAD therapy, namely drive line infection and thromboembolic events leading to stroke. This thesis focuses on a surgical maneuver to address the second of these issues, guided by previous steady flow hemodynamic studies that have shown the potential of tailoring the VAD outflow graft (VAD-OG) implantation in providing up to 50% reduction in embolization rates. In the current study, multi-scale pulsatile hemodynamics of the VAD bed is modeled and integrated in a fully automated multi-objective shape optimization scheme in which the VAD-OG anastomosis along the Ascending Aorta (AA) is optimized to minimize the objective function which include thromboembolic events to the cerebral vessels and wall shear stress (WSS). The model is driven by a time dependent pressure and flow boundary conditions located at the boundaries of the 3D domain through a 50 degree of freedom 0D lumped parameter model (LPM). The model includes a time dependent multi-scale Computational Fluid Dynamics (CFD) analysis of a patient specific geometry. Blood rheology is modeled as using the non-Newtonian Carreua-Yasuda model, while the hemodynamics are that of a laminar and constant density fluid. The pulsatile hemodynamics are resolved using the commercial CFD solver StarCCM+ while a Lagrangian particle tracking scheme is used to track constant density particles modeling thromobi released from the cannula to determine embolization rated of thrombi. The results show that cannula anastomosis orientation plays a large role when minimizing the objective function for patient derived aortic bed geometry used in this study. The scheme determined the optimal location of the cannula is located at 5.5 cm from the aortic root, cannula angle at 90 degrees and coronal angle at 8 degrees along the AA with a peak surface average WSS of 55.97 dy/cm2 and stroke percentile of 12.51%. A Pareto front was generated showing the range of 9.7% to 44.08% for stroke and WSS of 55.97 to 81.47 dy/cm2 ranged over 22 implantation configurations for the specific case studied. These results will further assist in the treatment planning for clinicians when implementing a LVAD.
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Date Issued
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2019
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Identifier
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CFE0007833, ucf:52827
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Format
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Document (PDF)
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PURL
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http://purl.flvc.org/ucf/fd/CFE0007833
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Title
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Mechanisms of Alpha-Synuclein-Induced Neurodegenertaion in Parkinson's Disease and Stroke.
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Creator
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Belal, Cherine, Chan, Sic, Ebert, Steven, Self, William, Teter, Kenneth, University of Central Florida
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Abstract / Description
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Parkinson's disease (PD) is a debilitating neurodegenerative disorder affecting one million Americans. Despite its social and economic impact, the pathological cascades that lead to neuron dysfunction and degeneration in PD are poorly understood. Endoplasmic reticulum (ER) stress has been implicated as an initiator or contributing factor in neurodegenerative diseases including PD. The ER is an organelle central to protein folding and intracellular Ca2+ homeostasis. Perturbations of these...
Show moreParkinson's disease (PD) is a debilitating neurodegenerative disorder affecting one million Americans. Despite its social and economic impact, the pathological cascades that lead to neuron dysfunction and degeneration in PD are poorly understood. Endoplasmic reticulum (ER) stress has been implicated as an initiator or contributing factor in neurodegenerative diseases including PD. The ER is an organelle central to protein folding and intracellular Ca2+ homeostasis. Perturbations of these functions result in ER stress and upregulation of ER stress proteins, of which some have been implicated in counteracting ER stress-induced cell death. The mechanisms that lead to ER stress and how ER stress proteins contribute to the degenerative cascades remain unclear but their understanding is critical to devising effective therapies for PD. Both the accumulation of mutant a-synuclein (aSyn), which causes an inherited form of PD, and the inhibition of mitochondrial complex I function by PD-inducing neurotoxin lead to ER stress. The critical involvement of ER stress in experimental models of PD supports its potential relevance to PD pathogenesis and led us to test the hypothesis whether the homocysteine-inducible ER protein (Herp), an ubiquitin-like domain (UBD) containing ER-resident protein, can counteract mutant Alpha Syn- and neurotoxin- induced pathological cascades.
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Date Issued
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2011
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Identifier
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CFE0004470, ucf:49310
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Format
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Document (PDF)
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PURL
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http://purl.flvc.org/ucf/fd/CFE0004470
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Title
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Physical-Virtual Patient Simulators: Bringing Tangible Humanity to Simulated Patients.
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Creator
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Daher, Salam, Welch, Gregory, Gonzalez, Laura, Cendan, Juan, Proctor, Michael, University of Central Florida
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Abstract / Description
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In lieu of real patients, healthcare educators frequently use simulated patients. Simulated patients can be realized in physical form, such as mannequins and trained human actors, or virtual form, such as via computer graphics presented on two-dimensional screens or head-mounted displays. Each of these alone has its strengths and weaknesses. I introduce a new class of physical-virtual patient (PVP) simulators that combine strengths of both forms by combining the flexibility and richness of...
Show moreIn lieu of real patients, healthcare educators frequently use simulated patients. Simulated patients can be realized in physical form, such as mannequins and trained human actors, or virtual form, such as via computer graphics presented on two-dimensional screens or head-mounted displays. Each of these alone has its strengths and weaknesses. I introduce a new class of physical-virtual patient (PVP) simulators that combine strengths of both forms by combining the flexibility and richness of virtual patients with tangible characteristics of a human-shaped physical form that can also exhibit a range of multi-sensory cues, including visual cues (e.g., capillary refill and facial expressions), auditory cues (e.g., verbal responses and heart sounds), and tactile cues (e.g., localized temperature and pulse). This novel combination of integrated capabilities can improve patient simulation outcomes. In my Ph.D. work I focus on three primary areas of related research. First, I describe the realization of the technology for PVPs and results from two user-studies to evaluate the importance of dynamic visuals and human-shaped physical form in terms of perception, behavior, cognition, emotions, and learning.Second, I present a general method to numerically evaluate the compatibility of any simulator-scenario pair in terms of importance and fidelity of cues. This method has the potential to make logistical, economic, and educational impacts on the choices of utilizing existing simulators.Finally, I describe a method for increasing human perception of simulated humans by exposing participants to the simulated human taking part in a short, engaging conversation prior to the simulation.
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Date Issued
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2018
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Identifier
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CFE0007750, ucf:52402
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Format
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Document (PDF)
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PURL
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http://purl.flvc.org/ucf/fd/CFE0007750